Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders
OBJECTIVE: Local injection of botulinum toxin is a highly effective treatment option for a wide range of movement disorders and there are reliable sources of information on its indications, effects and safety in clinical practice. In this study, we report our experience with botulinum toxin in the t...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2012-12-01
|
| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-26097 |
| _version_ | 1797912039622967296 |
|---|---|
| author | Arzu Çoban Zeliha Matur Haşmet A. Hanağası Yeşim Parman |
| author_facet | Arzu Çoban Zeliha Matur Haşmet A. Hanağası Yeşim Parman |
| author_sort | Arzu Çoban |
| collection | DOAJ |
| description | OBJECTIVE: Local injection of botulinum toxin is a highly effective treatment option for a wide range of movement disorders and there are reliable sources of information on its indications, effects and safety in clinical practice. In this study, we report our experience with botulinum toxin in the treatment of facial region disorders.
METHODS: Patients who had been followed in the Botulinum Toxin Outpatient Clinic of the Neurology Department were retrospectively evaluated. Two preparations of botulinum toxin type A (BT-A) were used. The efficacy of BT-A injections was rated according to the improvement in symptoms as follows: marked - 75-100% improvement, good - 50-74%, moderate - 25-49%, and insufficient - less than 25% symptom relief.
RESULTS: One hundred eighty-two patients (73 male, 109 female) with various facial region disorders were included. The efficacy rates for patients who had very good and good improvement were high in the treatment of blepharospasm, hemifacial spasm, facial synkinesis, and Meige syndrome and moderate for oromandibular dystonia and hypersalivation. Ptosis was the most common side effect.
CONCLUSION: According to our results, botulinum toxin was very effective treatment for blepharospasm, Meige syndrome, hemifacial spasm and facial synkinesis, whereas it demonstrated good efficacy in oromandibular dystonia and hypersalivation |
| first_indexed | 2024-04-10T11:50:05Z |
| format | Article |
| id | doaj.art-085540302236449e8047c60b5fc2e64a |
| institution | Directory Open Access Journal |
| issn | 1301-062X 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T11:50:05Z |
| publishDate | 2012-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-085540302236449e8047c60b5fc2e64a2023-02-15T16:17:09ZengGalenos YayineviTürk Nöroloji Dergisi1301-062X1309-25452012-12-0118415516110.4274/Tnd.26097Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region DisordersArzu Çoban0Zeliha Matur1Haşmet A. Hanağası2Yeşim Parman3Department Of Neurology, Balıkesir University Medical Faculty, Balıkesir, TurkeyDepartment Of Neurology, Istanbul University, Istanbul Medical Faculty,ıstanbul, TurkeyDepartment Of Neurology, Istanbul University, Istanbul Medical Faculty,ıstanbul, TurkeyDepartment Of Neurology, Istanbul University, Istanbul Medical Faculty,ıstanbul, TurkeyOBJECTIVE: Local injection of botulinum toxin is a highly effective treatment option for a wide range of movement disorders and there are reliable sources of information on its indications, effects and safety in clinical practice. In this study, we report our experience with botulinum toxin in the treatment of facial region disorders. METHODS: Patients who had been followed in the Botulinum Toxin Outpatient Clinic of the Neurology Department were retrospectively evaluated. Two preparations of botulinum toxin type A (BT-A) were used. The efficacy of BT-A injections was rated according to the improvement in symptoms as follows: marked - 75-100% improvement, good - 50-74%, moderate - 25-49%, and insufficient - less than 25% symptom relief. RESULTS: One hundred eighty-two patients (73 male, 109 female) with various facial region disorders were included. The efficacy rates for patients who had very good and good improvement were high in the treatment of blepharospasm, hemifacial spasm, facial synkinesis, and Meige syndrome and moderate for oromandibular dystonia and hypersalivation. Ptosis was the most common side effect. CONCLUSION: According to our results, botulinum toxin was very effective treatment for blepharospasm, Meige syndrome, hemifacial spasm and facial synkinesis, whereas it demonstrated good efficacy in oromandibular dystonia and hypersalivationhttp://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-26097Botulinum toxin type-Afacial region disordersefficacy |
| spellingShingle | Arzu Çoban Zeliha Matur Haşmet A. Hanağası Yeşim Parman Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders Türk Nöroloji Dergisi Botulinum toxin type-A facial region disorders efficacy |
| title | Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders |
| title_full | Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders |
| title_fullStr | Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders |
| title_full_unstemmed | Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders |
| title_short | Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders |
| title_sort | efficacy of botulinum toxin injections in the treatment of various types of facial region disorders |
| topic | Botulinum toxin type-A facial region disorders efficacy |
| url | http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-26097 |
| work_keys_str_mv | AT arzucoban efficacyofbotulinumtoxininjectionsinthetreatmentofvarioustypesoffacialregiondisorders AT zelihamatur efficacyofbotulinumtoxininjectionsinthetreatmentofvarioustypesoffacialregiondisorders AT hasmetahanagası efficacyofbotulinumtoxininjectionsinthetreatmentofvarioustypesoffacialregiondisorders AT yesimparman efficacyofbotulinumtoxininjectionsinthetreatmentofvarioustypesoffacialregiondisorders |