Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh
A cross-sectional study was conducted to determine the seroprevalence of the Peste des Petits Ruminant (PPR) virus (PPRV) in sheep populations and to determine the potential epidemiological risk factors associated with this infection. Between October 2014 and March 2017, 2420 sheep serum samples wer...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Saudi Journal of Biological Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X23000104 |
| _version_ | 1811157852995190784 |
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| author | Mohammad Mojibur Rahman Abdullah Al Momen Sabuj Md. Saiful Islam Md. Alimul Islam Jahangir Alam Md. Ershaduzzaman Sukumar Saha |
| author_facet | Mohammad Mojibur Rahman Abdullah Al Momen Sabuj Md. Saiful Islam Md. Alimul Islam Jahangir Alam Md. Ershaduzzaman Sukumar Saha |
| author_sort | Mohammad Mojibur Rahman |
| collection | DOAJ |
| description | A cross-sectional study was conducted to determine the seroprevalence of the Peste des Petits Ruminant (PPR) virus (PPRV) in sheep populations and to determine the potential epidemiological risk factors associated with this infection. Between October 2014 and March 2017, 2420 sheep serum samples were collected from ten selected PPR outbreak-prone districts in Bangladesh. The collected sera were analysed by competitive enzyme-linked immunosorbent assay (cELISA) test to detect antibodies against PPR. A previously designed disease report form was used to gather data on important epidemiological risk factors, and a risk analysis was performed to ascertain their association with PPRV infection. By cELISA, 44.3 % (95 % confidence interval:42.4–46.4 %) of sheep sera were positive for PPRV antibodies against PPR. In univariate analysis, the Bagerhat district had significantly higher seropositivity (54.1 %, 156/288) than other districts. Moreover, significantly higher (p < 0.05) seropositivity was found in the Jamuna River Basin (49.1 %, 217/442) compared to other ecological zones, in crossbreeds (60 %; 600/1000) related to native sheep, in males (69.8 %, 289/414) associated with females, in imported sheep (74.3 %, 223/300) compared to other sources, and in winter (57.2 %, 527/920) than in other seasons. In the multivariate logistic regression model, six possible risk factors were identified: study location, ecological zone, breed, sex, source, and season. The high seroprevalence of PPRV is significantly associated with several risk factors, suggesting that PPR is epizootic throughout the country. |
| first_indexed | 2024-04-10T05:14:27Z |
| format | Article |
| id | doaj.art-08564d9c74c94d92b301efc95399b1d1 |
| institution | Directory Open Access Journal |
| issn | 1319-562X |
| language | English |
| last_indexed | 2024-04-10T05:14:27Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Journal of Biological Sciences |
| spelling | doaj.art-08564d9c74c94d92b301efc95399b1d12023-03-09T04:12:48ZengElsevierSaudi Journal of Biological Sciences1319-562X2023-03-01303103565Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in BangladeshMohammad Mojibur Rahman0Abdullah Al Momen Sabuj1Md. Saiful Islam2Md. Alimul Islam3Jahangir Alam4Md. Ershaduzzaman5Sukumar Saha6Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh; Bangladesh Civil Service Livestock Academy, Savar, Dhaka 1349, BangladeshDepartment of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, BangladeshDepartment of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, BangladeshDepartment of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, BangladeshAnimal Biotechnology Division, National Institute of Biotechnology, Ganakbari, Ashulia, Savar, Dhaka 1349, BangladeshKrishi Gobeshona Foundation, Bangladesh Agricultural Research Council, Farmgate, Dhaka 1215, BangladeshDepartment of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh; Corresponding author at: Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.A cross-sectional study was conducted to determine the seroprevalence of the Peste des Petits Ruminant (PPR) virus (PPRV) in sheep populations and to determine the potential epidemiological risk factors associated with this infection. Between October 2014 and March 2017, 2420 sheep serum samples were collected from ten selected PPR outbreak-prone districts in Bangladesh. The collected sera were analysed by competitive enzyme-linked immunosorbent assay (cELISA) test to detect antibodies against PPR. A previously designed disease report form was used to gather data on important epidemiological risk factors, and a risk analysis was performed to ascertain their association with PPRV infection. By cELISA, 44.3 % (95 % confidence interval:42.4–46.4 %) of sheep sera were positive for PPRV antibodies against PPR. In univariate analysis, the Bagerhat district had significantly higher seropositivity (54.1 %, 156/288) than other districts. Moreover, significantly higher (p < 0.05) seropositivity was found in the Jamuna River Basin (49.1 %, 217/442) compared to other ecological zones, in crossbreeds (60 %; 600/1000) related to native sheep, in males (69.8 %, 289/414) associated with females, in imported sheep (74.3 %, 223/300) compared to other sources, and in winter (57.2 %, 527/920) than in other seasons. In the multivariate logistic regression model, six possible risk factors were identified: study location, ecological zone, breed, sex, source, and season. The high seroprevalence of PPRV is significantly associated with several risk factors, suggesting that PPR is epizootic throughout the country.http://www.sciencedirect.com/science/article/pii/S1319562X23000104SheepPPREpidemiologyRisk factorscELISASeroprevalence |
| spellingShingle | Mohammad Mojibur Rahman Abdullah Al Momen Sabuj Md. Saiful Islam Md. Alimul Islam Jahangir Alam Md. Ershaduzzaman Sukumar Saha Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh Saudi Journal of Biological Sciences Sheep PPR Epidemiology Risk factors cELISA Seroprevalence |
| title | Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh |
| title_full | Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh |
| title_fullStr | Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh |
| title_full_unstemmed | Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh |
| title_short | Serological study and risk factor analysis on Peste des Petits Ruminants in sheep in Bangladesh |
| title_sort | serological study and risk factor analysis on peste des petits ruminants in sheep in bangladesh |
| topic | Sheep PPR Epidemiology Risk factors cELISA Seroprevalence |
| url | http://www.sciencedirect.com/science/article/pii/S1319562X23000104 |
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