The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data
Background Meta-analyses show efficacy of mindfulness-based cognitive therapy (MBCT) in terms of relapse prevention and depressive symptom reduction in patients with major depressive disorder (MDD). However, most studies have been conducted in controlled research settings. Aims We aimed to investig...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2020-11-01
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| Series: | BJPsych Open |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472420001180/type/journal_article |
| _version_ | 1811156982080471040 |
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| author | Dirk E.M. Geurts Felix R. Compen Marleen H.C.T. Van Beek Anne E.M. Speckens |
| author_facet | Dirk E.M. Geurts Felix R. Compen Marleen H.C.T. Van Beek Anne E.M. Speckens |
| author_sort | Dirk E.M. Geurts |
| collection | DOAJ |
| description | Background
Meta-analyses show efficacy of mindfulness-based cognitive therapy (MBCT) in terms of relapse prevention and depressive symptom reduction in patients with major depressive disorder (MDD). However, most studies have been conducted in controlled research settings.
Aims
We aimed to investigate the effectiveness of MBCT in patients with MDD presenting in real-world clinical practice. Moreover, we assessed whether guideline recommendations for MBCT allocation in regard to recurrence and remission status of MDD hold in clinical practice.
Method
This study assessed a naturalistic cohort of patients with (recurrent) MDD, either current or in remission (n = 765), who received MBCT in a university hospital out-patient clinic in The Netherlands. Outcome measures were self-reported depressive symptoms, worry, mindfulness skills and self-compassion. Predictors were MDD recurrence and remission status, and clinical and sociodemographic variables. Outcome and predictor analyses were conducted with linear regression.
Results
MBCT adherence was high (94%). Patients with a lower level of education had a higher chance of non-adherence. Attending more sessions positively influenced improvement in depressive symptoms. Depressive symptoms significantly reduced from pre- to post-MBCT (Δ mean = 7.7, 95%CI = 7.0–8.5, Cohen's d = 0.75). Improvement of depressive symptoms was independent from MDD recurrence and remission status. Unemployed patients showed less favourable outcomes. Worry, mindfulness skills and self-compassion all significantly improved. These improvements were related to changes in depressive symptoms.
Conclusions
Previous efficacy results in controlled research settings are maintained in clinical practice. Results illustrate that MBCT is effective in routine clinical practice for patients suffering from MDD, irrespective of MDD recurrence and remission status.
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| first_indexed | 2024-04-10T04:58:43Z |
| format | Article |
| id | doaj.art-085675c5b37845caa97774a8e8fdf9a4 |
| institution | Directory Open Access Journal |
| issn | 2056-4724 |
| language | English |
| last_indexed | 2024-04-10T04:58:43Z |
| publishDate | 2020-11-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj.art-085675c5b37845caa97774a8e8fdf9a42023-03-09T12:29:04ZengCambridge University PressBJPsych Open2056-47242020-11-01610.1192/bjo.2020.118The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring dataDirk E.M. Geurts0https://orcid.org/0000-0002-2505-1301Felix R. Compen1Marleen H.C.T. Van Beek2Anne E.M. Speckens3Department of Psychiatry, Radboud University; and Donders Institute for Brain, Cognition and Behavior, Radboud University, The NetherlandsDepartment of Psychiatry, Radboud University; and Donders Institute for Brain, Cognition and Behavior, Radboud University, The NetherlandsDepartment of Psychiatry, Radboud University; and Donders Institute for Brain, Cognition and Behavior, Radboud University, The NetherlandsDepartment of Psychiatry, Radboud University; and Donders Institute for Brain, Cognition and Behavior, Radboud University, The NetherlandsBackground Meta-analyses show efficacy of mindfulness-based cognitive therapy (MBCT) in terms of relapse prevention and depressive symptom reduction in patients with major depressive disorder (MDD). However, most studies have been conducted in controlled research settings. Aims We aimed to investigate the effectiveness of MBCT in patients with MDD presenting in real-world clinical practice. Moreover, we assessed whether guideline recommendations for MBCT allocation in regard to recurrence and remission status of MDD hold in clinical practice. Method This study assessed a naturalistic cohort of patients with (recurrent) MDD, either current or in remission (n = 765), who received MBCT in a university hospital out-patient clinic in The Netherlands. Outcome measures were self-reported depressive symptoms, worry, mindfulness skills and self-compassion. Predictors were MDD recurrence and remission status, and clinical and sociodemographic variables. Outcome and predictor analyses were conducted with linear regression. Results MBCT adherence was high (94%). Patients with a lower level of education had a higher chance of non-adherence. Attending more sessions positively influenced improvement in depressive symptoms. Depressive symptoms significantly reduced from pre- to post-MBCT (Δ mean = 7.7, 95%CI = 7.0–8.5, Cohen's d = 0.75). Improvement of depressive symptoms was independent from MDD recurrence and remission status. Unemployed patients showed less favourable outcomes. Worry, mindfulness skills and self-compassion all significantly improved. These improvements were related to changes in depressive symptoms. Conclusions Previous efficacy results in controlled research settings are maintained in clinical practice. Results illustrate that MBCT is effective in routine clinical practice for patients suffering from MDD, irrespective of MDD recurrence and remission status. https://www.cambridge.org/core/product/identifier/S2056472420001180/type/journal_articleDepressive disordersgroup psychotherapyoutcome studiesout-patient treatmentcomorbidity |
| spellingShingle | Dirk E.M. Geurts Felix R. Compen Marleen H.C.T. Van Beek Anne E.M. Speckens The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data BJPsych Open Depressive disorders group psychotherapy outcome studies out-patient treatment comorbidity |
| title | The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data |
| title_full | The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data |
| title_fullStr | The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data |
| title_full_unstemmed | The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data |
| title_short | The effectiveness of mindfulness-based cognitive therapy for major depressive disorder: evidence from routine outcome monitoring data |
| title_sort | effectiveness of mindfulness based cognitive therapy for major depressive disorder evidence from routine outcome monitoring data |
| topic | Depressive disorders group psychotherapy outcome studies out-patient treatment comorbidity |
| url | https://www.cambridge.org/core/product/identifier/S2056472420001180/type/journal_article |
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