Connexins in Cancer, the Possible Role of Connexin46 as a Cancer Stem Cell-Determining Protein

Connexins in Cancer, the Possible Role of Connexin46 as a Cancer Stem Cell-Determining Protein

Cancer is a widespread and incurable disease caused by genetic mutations, leading to uncontrolled cell proliferation and metastasis. Connexins (Cx) are transmembrane proteins that facilitate intercellular communication via hemichannels and gap junction channels. Among them, Cx46 is found mostly in t...

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Bibliographic Details
Main Authors: Isidora M. León-Fuentes, María G. Salgado-Gil, María S. Novoa, Mauricio A. Retamal
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
Connexin46
GJA3
cancer stem cells
breast cancer
gap junction channels
Online Access:https://www.mdpi.com/2218-273X/13/10/1460

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