Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples

Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples

Abstract Mucus hypersecretion contributes to lung function impairment observed in COPD (chronic obstructive pulmonary disease), a tobacco smoking-related disease. A detailed mucus hypersecretion adverse outcome pathway (AOP) has been constructed from literature reviews, experimental and clinical dat...

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Bibliographic Details
Main Authors: Emmanuel Minet, Linsey E. Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro, Francisco De Abreu e Lima, Tomasz Jaunky, Simone Santopietro, Damien Breheny, Marianna D. Gaça
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85345-9

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