Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study
Background: Dysphagia is a common and clinically significant complication of ischemic stroke. The prevalence and risk factors for dysphagia may vary at different stages following an ischemic stroke. Methods: This study included patients with acute and chronic ischemic stroke who were treated at the...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024006133 |
| _version_ | 1797328570664615936 |
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| author | Lin Mao Juehan Wang Yubo Li JinJin Zheng Denghuang Fan Shuang Wei Xiaohong Wu Xiaofeng Yang Daming Wang |
| author_facet | Lin Mao Juehan Wang Yubo Li JinJin Zheng Denghuang Fan Shuang Wei Xiaohong Wu Xiaofeng Yang Daming Wang |
| author_sort | Lin Mao |
| collection | DOAJ |
| description | Background: Dysphagia is a common and clinically significant complication of ischemic stroke. The prevalence and risk factors for dysphagia may vary at different stages following an ischemic stroke. Methods: This study included patients with acute and chronic ischemic stroke who were treated at the Department of Rehabilitation, First Affiliated Hospital, Zhejiang University School of Medicine from 2019 to 2022. Various demographic, clinical, and laboratory parameters were collected, and statistical analyses were performed to investigate their association with dysphagia. Results: Among the 399 ischemic stroke patients included in the study, 165 (41.4 %) experienced dysphagia, with 72 (38.7 %) in the acute phase and 93 (43.7 %) in the chronic phase. Univariate analysis revealed significant associations (p < 0.05) between dysphagia and factors such as pulmonary infection, aphasia, NIHSS score, ADL score, NLR score, lower extremity Brunnstrom's stages, and sit-to-stand balance. Multiple logistic regression analysis, after adjusting for confounding factors, identified the ADL score as an independent predictor of dysphagia. These findings were consistent across three time-windows: the acute phase, the chronic phase, and 180 days after stroke onset. Additionally, the lymphocyte count and pulmonary infection were identified as potential independent indicators. Conclusions: This study investigated the prevalence and risk factors for dysphagia in ischemic stroke patients at different time-windows. A low ADL score (<40) may serve as a valuable and reliable predictor for poststroke dysphagia in clinical settings. |
| first_indexed | 2024-03-08T06:54:35Z |
| format | Article |
| id | doaj.art-085f6149802d4fe0bb6ca282639449d3 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:54:35Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-085f6149802d4fe0bb6ca282639449d32024-02-03T06:37:55ZengElsevierHeliyon2405-84402024-01-01102e24582Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort studyLin Mao0Juehan Wang1Yubo Li2JinJin Zheng3Denghuang Fan4Shuang Wei5Xiaohong Wu6Xiaofeng Yang7Daming Wang8Department of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaInformation and Electronic Engineering College, Zhejiang University School, Hangzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaEmergency and Trauma Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Corresponding author.Department of Rehabilitation Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Corresponding author.Background: Dysphagia is a common and clinically significant complication of ischemic stroke. The prevalence and risk factors for dysphagia may vary at different stages following an ischemic stroke. Methods: This study included patients with acute and chronic ischemic stroke who were treated at the Department of Rehabilitation, First Affiliated Hospital, Zhejiang University School of Medicine from 2019 to 2022. Various demographic, clinical, and laboratory parameters were collected, and statistical analyses were performed to investigate their association with dysphagia. Results: Among the 399 ischemic stroke patients included in the study, 165 (41.4 %) experienced dysphagia, with 72 (38.7 %) in the acute phase and 93 (43.7 %) in the chronic phase. Univariate analysis revealed significant associations (p < 0.05) between dysphagia and factors such as pulmonary infection, aphasia, NIHSS score, ADL score, NLR score, lower extremity Brunnstrom's stages, and sit-to-stand balance. Multiple logistic regression analysis, after adjusting for confounding factors, identified the ADL score as an independent predictor of dysphagia. These findings were consistent across three time-windows: the acute phase, the chronic phase, and 180 days after stroke onset. Additionally, the lymphocyte count and pulmonary infection were identified as potential independent indicators. Conclusions: This study investigated the prevalence and risk factors for dysphagia in ischemic stroke patients at different time-windows. A low ADL score (<40) may serve as a valuable and reliable predictor for poststroke dysphagia in clinical settings.http://www.sciencedirect.com/science/article/pii/S2405844024006133DysphagiaIschemic strokeRisk factorPost-stroke complicationsCohort study |
| spellingShingle | Lin Mao Juehan Wang Yubo Li JinJin Zheng Denghuang Fan Shuang Wei Xiaohong Wu Xiaofeng Yang Daming Wang Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study Heliyon Dysphagia Ischemic stroke Risk factor Post-stroke complications Cohort study |
| title | Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study |
| title_full | Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study |
| title_fullStr | Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study |
| title_full_unstemmed | Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study |
| title_short | Risk factors for dysphagia in patients with acute and chronic ischemic stroke: A retrospective cohort study |
| title_sort | risk factors for dysphagia in patients with acute and chronic ischemic stroke a retrospective cohort study |
| topic | Dysphagia Ischemic stroke Risk factor Post-stroke complications Cohort study |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024006133 |
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