Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique
Nowadays in radiotherapy, much effort is taken to minimize the irradiated volume and consequently minimize doses to healthy tissues. In our work, we tested the hypothesis that the mean dose distribution calculated from a few first fractions can serve as prediction of the cumulated dose distribution,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2016-03-01
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| Series: | Nukleonika |
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| Online Access: | http://www.degruyter.com/view/j/nuka.2016.6.issue-1/nuka-2016-0005/nuka-2016-0005.xml?format=INT |
| _version_ | 1828136541652779008 |
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| author | Giżyńska Marta Blatkiewicz Dorota Czyżew Beata Gałecki Maciej Gil-Ulkowska Małgorzata Kukołowicz Paweł |
| author_facet | Giżyńska Marta Blatkiewicz Dorota Czyżew Beata Gałecki Maciej Gil-Ulkowska Małgorzata Kukołowicz Paweł |
| author_sort | Giżyńska Marta |
| collection | DOAJ |
| description | Nowadays in radiotherapy, much effort is taken to minimize the irradiated volume and consequently minimize doses to healthy tissues. In our work, we tested the hypothesis that the mean dose distribution calculated from a few first fractions can serve as prediction of the cumulated dose distribution, representing the whole treatment. We made our tests for 25 prostate cancer patients treated with three orthogonal fields technique. We did a comparison of dose distribution calculated as a sum of dose distribution from each fraction with a dose distribution calculated with isocenter shifted for a mean setup error from a few first fractions. The cumulative dose distribution and predicted dose distributions are similar in terms of gamma (3 mm 3%) analysis, under condition that we know setup error from seven first fractions. We showed that the dose distribution calculated for the original plan with the isocenter shifted to the point, defined as the original isocenter corrected of the mean setup error estimated from the first seven fractions supports our hypothesis, i.e. can serve as a prediction for cumulative dose distribution. |
| first_indexed | 2024-04-11T18:06:01Z |
| format | Article |
| id | doaj.art-0862ccb8ae3243bbb509f2cb318d0fc1 |
| institution | Directory Open Access Journal |
| issn | 0029-5922 |
| language | English |
| last_indexed | 2024-04-11T18:06:01Z |
| publishDate | 2016-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Nukleonika |
| spelling | doaj.art-0862ccb8ae3243bbb509f2cb318d0fc12022-12-22T04:10:20ZengSciendoNukleonika0029-59222016-03-01611151810.1515/nuka-2016-0005nuka-2016-0005Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT techniqueGiżyńska Marta0Blatkiewicz Dorota1Czyżew Beata2Gałecki Maciej3Gil-Ulkowska Małgorzata4Kukołowicz Paweł5Department of Medical Physics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 15B Wawelska Str., 02-034 Warsaw, Poland and Biomedical Physics Division, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 5 Pasteura Str., 02-093 Warsaw, PolandDepartment of Medical Physics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 15B Wawelska Str., 02-034 Warsaw, PolandDepartment of Medical Physics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 15B Wawelska Str., 02-034 Warsaw, PolandBiomedical Physics Division, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 5 Pasteura Str., 02-093 Warsaw, PolandDepartment of Medical Physics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 15B Wawelska Str., 02-034 Warsaw, PolandDepartment of Medical Physics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, 15B Wawelska Str., 02-034 Warsaw, PolandNowadays in radiotherapy, much effort is taken to minimize the irradiated volume and consequently minimize doses to healthy tissues. In our work, we tested the hypothesis that the mean dose distribution calculated from a few first fractions can serve as prediction of the cumulated dose distribution, representing the whole treatment. We made our tests for 25 prostate cancer patients treated with three orthogonal fields technique. We did a comparison of dose distribution calculated as a sum of dose distribution from each fraction with a dose distribution calculated with isocenter shifted for a mean setup error from a few first fractions. The cumulative dose distribution and predicted dose distributions are similar in terms of gamma (3 mm 3%) analysis, under condition that we know setup error from seven first fractions. We showed that the dose distribution calculated for the original plan with the isocenter shifted to the point, defined as the original isocenter corrected of the mean setup error estimated from the first seven fractions supports our hypothesis, i.e. can serve as a prediction for cumulative dose distribution.http://www.degruyter.com/view/j/nuka.2016.6.issue-1/nuka-2016-0005/nuka-2016-0005.xml?format=INT3D-CRTcumulative dosedose predictionsetup errorindividualized margins |
| spellingShingle | Giżyńska Marta Blatkiewicz Dorota Czyżew Beata Gałecki Maciej Gil-Ulkowska Małgorzata Kukołowicz Paweł Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique Nukleonika 3D-CRT cumulative dose dose prediction setup error individualized margins |
| title | Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique |
| title_full | Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique |
| title_fullStr | Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique |
| title_full_unstemmed | Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique |
| title_short | Prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3D-CRT technique |
| title_sort | prediction of the cumulated dose for external beam irradiation of prostate cancer patients with 3d crt technique |
| topic | 3D-CRT cumulative dose dose prediction setup error individualized margins |
| url | http://www.degruyter.com/view/j/nuka.2016.6.issue-1/nuka-2016-0005/nuka-2016-0005.xml?format=INT |
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