Neurotrophic factors in tension-type headache
Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study includ...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2015-05-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000500009&lng=en&tlng=en |
| _version_ | 1818479807474696192 |
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| author | Renan B. Domingues Halina Duarte Natália P. Rocha Antonio L. Teixeira |
| author_facet | Renan B. Domingues Halina Duarte Natália P. Rocha Antonio L. Teixeira |
| author_sort | Renan B. Domingues |
| collection | DOAJ |
| description | Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH. |
| first_indexed | 2024-12-10T11:15:31Z |
| format | Article |
| id | doaj.art-0864552e4f91477ea392037cc929156d |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-10T11:15:31Z |
| publishDate | 2015-05-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-0864552e4f91477ea392037cc929156d2022-12-22T01:51:12ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272015-05-0173542042410.1590/0004-282X20150000S0004-282X2015000500009Neurotrophic factors in tension-type headacheRenan B. DominguesHalina DuarteNatália P. RochaAntonio L. TeixeiraNeurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000500009&lng=en&tlng=encefaleia do tipo tensionalfatores neurotróficosdepressãoansiedade |
| spellingShingle | Renan B. Domingues Halina Duarte Natália P. Rocha Antonio L. Teixeira Neurotrophic factors in tension-type headache Arquivos de Neuro-Psiquiatria cefaleia do tipo tensional fatores neurotróficos depressão ansiedade |
| title | Neurotrophic factors in tension-type headache |
| title_full | Neurotrophic factors in tension-type headache |
| title_fullStr | Neurotrophic factors in tension-type headache |
| title_full_unstemmed | Neurotrophic factors in tension-type headache |
| title_short | Neurotrophic factors in tension-type headache |
| title_sort | neurotrophic factors in tension type headache |
| topic | cefaleia do tipo tensional fatores neurotróficos depressão ansiedade |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000500009&lng=en&tlng=en |
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