α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy

α-Lipoic acid (thioctic) (ALA) is the most applicable pharmacological drug for treatment of diabetic polyneuropathy. The articles explores the results of experimental studies on α-Lipoic acid effect upon formation mechanisms of peripheral nerves affection under hyperglycemia and also the data of num...

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Main Authors: I. A. Strokov, A. S. Phokina
Format: Article
Language:Russian
Published: Remedium Group LLC 2016-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/1577
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author I. A. Strokov
A. S. Phokina
author_facet I. A. Strokov
A. S. Phokina
author_sort I. A. Strokov
collection DOAJ
description α-Lipoic acid (thioctic) (ALA) is the most applicable pharmacological drug for treatment of diabetic polyneuropathy. The articles explores the results of experimental studies on α-Lipoic acid effect upon formation mechanisms of peripheral nerves affection under hyperglycemia and also the data of numerous randomized controlled trials and meta-analyses on studying ALA efficiency under symptomatic diabetic polyneuropathy. It was proved that amelioration of patients with diabetic polyneuropathy is observed both while using ALA infusions and tableted form of the drug. The authors conclude that α-lipoic acid is a drug for treatment of pathogenetic development mechanisms of diabetic polyneuropathy with the most demonstrated efficiency.
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spelling doaj.art-086492b5f10241c8a56ccfad5c119c612023-04-23T06:56:52ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-01017283310.21518/2079-701X-2016-17-28-331570α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathyI. A. Strokov0A. S. Phokina1First Moscow State Medical UniversityFirst Moscow State Medical Universityα-Lipoic acid (thioctic) (ALA) is the most applicable pharmacological drug for treatment of diabetic polyneuropathy. The articles explores the results of experimental studies on α-Lipoic acid effect upon formation mechanisms of peripheral nerves affection under hyperglycemia and also the data of numerous randomized controlled trials and meta-analyses on studying ALA efficiency under symptomatic diabetic polyneuropathy. It was proved that amelioration of patients with diabetic polyneuropathy is observed both while using ALA infusions and tableted form of the drug. The authors conclude that α-lipoic acid is a drug for treatment of pathogenetic development mechanisms of diabetic polyneuropathy with the most demonstrated efficiency.https://www.med-sovet.pro/jour/article/view/1577diabetic polyneuropathypathogenesis of the diabetic polyneuropathypathogenetic therapy of diabetic polyneuropathyalpha-lipoic acidberlitionpain syndrome in diabetic polyneuropathy
spellingShingle I. A. Strokov
A. S. Phokina
α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
Медицинский совет
diabetic polyneuropathy
pathogenesis of the diabetic polyneuropathy
pathogenetic therapy of diabetic polyneuropathy
alpha-lipoic acid
berlition
pain syndrome in diabetic polyneuropathy
title α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
title_full α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
title_fullStr α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
title_full_unstemmed α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
title_short α-Lipoic acid as the main pharmacological drug for in- and outpatient treatment of diabetic polyneuropathy
title_sort α lipoic acid as the main pharmacological drug for in and outpatient treatment of diabetic polyneuropathy
topic diabetic polyneuropathy
pathogenesis of the diabetic polyneuropathy
pathogenetic therapy of diabetic polyneuropathy
alpha-lipoic acid
berlition
pain syndrome in diabetic polyneuropathy
url https://www.med-sovet.pro/jour/article/view/1577
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AT asphokina alipoicacidasthemainpharmacologicaldrugforinandoutpatienttreatmentofdiabeticpolyneuropathy