C2 Domains as Protein-Protein Interaction Modules in the Ciliary Transition Zone

C2 Domains as Protein-Protein Interaction Modules in the Ciliary Transition Zone

RPGR-interacting protein 1 (RPGRIP1) is mutated in the eye disease Leber congenital amaurosis (LCA) and its structural homolog, RPGRIP1-like (RPGRIP1L), is mutated in many different ciliopathies. Both are multidomain proteins that are predicted to interact with retinitis pigmentosa G-protein regulat...

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Bibliographic Details
Main Authors: Kim Remans, Marco Bürger, Ingrid R. Vetter, Alfred Wittinghofer
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714004434

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