Intravitreal low molecular weight heparin in PVR surgery.
<b>Purpose: </b> To evaluate the efficacy of low molecular weight heparin (LMWH) in prevention of postoperative fibrin formation following vitreoretinal surgery with proliferative vitreoretinopathy (PVR). <b> Material and Methods:</b> Thirty consecutive patients of retinal d...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2003-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2003;volume=51;issue=1;spage=67;epage=70;aulast=Kumar |
| _version_ | 1818158691126345728 |
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| author | Kumar Atul Nainiwal Sanjeev Sreenivas B |
| author_facet | Kumar Atul Nainiwal Sanjeev Sreenivas B |
| author_sort | Kumar Atul |
| collection | DOAJ |
| description | <b>Purpose: </b> To evaluate the efficacy of low molecular weight heparin (LMWH) in prevention of postoperative fibrin formation following vitreoretinal surgery with proliferative vitreoretinopathy (PVR). <b> Material and Methods:</b> Thirty consecutive patients of retinal detachment with advanced PVR were enrolled in the study. They were randomised to study and control groups (n = 15 each). Study group patients received vitreoretinal surgery with 5 IU/cc of LMWH in vitrectomy infusion fluid. The control group patients received vitroretinal surgery without heparin in the infusion fluid. Patients were followed up at 1 week, 1 month and 3 months after surgery. Postoperative bleeding, media clarity, best-corrected visual acuity and success of the surgery at the end of 3 months were compared between the two groups. <b> Results: </b> At each follow-up visit, the study group showed a better media clarity, which was statistically significant ( P = 0.0042). The study group had a 50% better chance of retinal reattachment compared to the control group. Five patients had intraoperative bleeding in the study group (33%) compared to 3 patients in the control group (20%). <b> Conclusion:</b> Use of intravitreal LMWH prevents postoperative fibrin formation and is beneficial in repair of retinal detachments with PVR. |
| first_indexed | 2024-12-11T15:34:06Z |
| format | Article |
| id | doaj.art-0865e7d8cb3342b4a11911974a7e1322 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-12-11T15:34:06Z |
| publishDate | 2003-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-0865e7d8cb3342b4a11911974a7e13222022-12-22T00:59:58ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47382003-01-015116770Intravitreal low molecular weight heparin in PVR surgery.Kumar AtulNainiwal SanjeevSreenivas B<b>Purpose: </b> To evaluate the efficacy of low molecular weight heparin (LMWH) in prevention of postoperative fibrin formation following vitreoretinal surgery with proliferative vitreoretinopathy (PVR). <b> Material and Methods:</b> Thirty consecutive patients of retinal detachment with advanced PVR were enrolled in the study. They were randomised to study and control groups (n = 15 each). Study group patients received vitreoretinal surgery with 5 IU/cc of LMWH in vitrectomy infusion fluid. The control group patients received vitroretinal surgery without heparin in the infusion fluid. Patients were followed up at 1 week, 1 month and 3 months after surgery. Postoperative bleeding, media clarity, best-corrected visual acuity and success of the surgery at the end of 3 months were compared between the two groups. <b> Results: </b> At each follow-up visit, the study group showed a better media clarity, which was statistically significant ( P = 0.0042). The study group had a 50% better chance of retinal reattachment compared to the control group. Five patients had intraoperative bleeding in the study group (33%) compared to 3 patients in the control group (20%). <b> Conclusion:</b> Use of intravitreal LMWH prevents postoperative fibrin formation and is beneficial in repair of retinal detachments with PVR.http://www.ijo.in/article.asp?issn=0301-4738;year=2003;volume=51;issue=1;spage=67;epage=70;aulast=KumarHeparinproliferative vitreoretinopathyPVR surgery |
| spellingShingle | Kumar Atul Nainiwal Sanjeev Sreenivas B Intravitreal low molecular weight heparin in PVR surgery. Indian Journal of Ophthalmology Heparin proliferative vitreoretinopathy PVR surgery |
| title | Intravitreal low molecular weight heparin in PVR surgery. |
| title_full | Intravitreal low molecular weight heparin in PVR surgery. |
| title_fullStr | Intravitreal low molecular weight heparin in PVR surgery. |
| title_full_unstemmed | Intravitreal low molecular weight heparin in PVR surgery. |
| title_short | Intravitreal low molecular weight heparin in PVR surgery. |
| title_sort | intravitreal low molecular weight heparin in pvr surgery |
| topic | Heparin proliferative vitreoretinopathy PVR surgery |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2003;volume=51;issue=1;spage=67;epage=70;aulast=Kumar |
| work_keys_str_mv | AT kumaratul intravitreallowmolecularweightheparininpvrsurgery AT nainiwalsanjeev intravitreallowmolecularweightheparininpvrsurgery AT sreenivasb intravitreallowmolecularweightheparininpvrsurgery |