Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.

BACKGROUND:Colorectal cancer (CRC) is the second leading cause of cancer deaths despite the fact that detection of this cancer in early stages results in over 90% survival rate. Currently less than 45% of at-risk individuals in the US are screened regularly, exposing a need for better screening test...

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Main Authors: Robert Grützmann, Bela Molnar, Christian Pilarsky, Jens K Habermann, Peter M Schlag, Hans D Saeger, Stephan Miehlke, Thomas Stolz, Fabian Model, Uwe J Roblick, Hans-Peter Bruch, Rainer Koch, Volker Liebenberg, Theo Devos, Xiaoling Song, Robert H Day, Andrew Z Sledziewski, Catherine Lofton-Day
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582436?pdf=render