Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model

Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model

Background: Non-metastatic muscle invasive urothelial bladder cancer (MIBC) has a poor prognosis and standard of care (SOC) includes neoadjuvant cisplatin-based chemotherapy (NAC) combined with cystectomy. Patients receiving NAC have at best <10% improvement in five-year overall survival compared...

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Bibliographic Details
Main Authors: Hugo Villanueva, Gabrielle A. Wells, Malachi T. Miller, Mariana Villanueva, Ravi Pathak, Patricia Castro, Michael M. Ittmann, Andrew G. Sikora, Seth P. Lerner
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Bladder cancer
CAM
Proteomics
Genomics
Chemotherapy
Kinase inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022038580

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022038580

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