Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system
The classical renin-angiotensin system (RAS) has an important role in the cardiovascular system and water homeostasis in the body. Recently, the existence of RAS with all of its components has been shown in the mammalian brain. RAS participates in many brain activities, including memory acquisition...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2022-04-01
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| Series: | Translational Neuroscience |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tnsci-2022-0215 |
| _version_ | 1811235768036753408 |
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| author | Sepehri Hamid Ganji Farzaneh Nazari Zahra Vahid Marzieh |
| author_facet | Sepehri Hamid Ganji Farzaneh Nazari Zahra Vahid Marzieh |
| author_sort | Sepehri Hamid |
| collection | DOAJ |
| description | The classical renin-angiotensin system (RAS) has an important role in the cardiovascular system and water homeostasis in the body. Recently, the existence of RAS with all of its components has been shown in the mammalian brain. RAS participates in many brain activities, including memory acquisition and consolidation. Since the cholinergic neurotransmission in the hippocampus is crucial for these functions, this study aims to evaluate the hippocampal angiotensin receptors (ATs) and choline acetyltransferase (ChAT) mRNA in the renovascular hypertensive rats in captopril- and losartan-treated hypertensive rats. |
| first_indexed | 2024-04-12T11:57:38Z |
| format | Article |
| id | doaj.art-08716080425f4e188e8d623f851efc6d |
| institution | Directory Open Access Journal |
| issn | 2081-6936 |
| language | English |
| last_indexed | 2024-04-12T11:57:38Z |
| publishDate | 2022-04-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Translational Neuroscience |
| spelling | doaj.art-08716080425f4e188e8d623f851efc6d2022-12-22T03:33:57ZengDe GruyterTranslational Neuroscience2081-69362022-04-01131727910.1515/tnsci-2022-0215Effects of Goldblatt hypertension on rats’ hippocampal cholinergic systemSepehri Hamid0Ganji Farzaneh1Nazari Zahra2Vahid Marzieh3Department of Physiology, Neuroscience Research Center, Golestan University of Medical Sciences, Gorgan, IranDepartment of Biology, Faculty of Science, Golestan University, Gorgan, IranDepartment of Biology, Faculty of Science, Golestan University, Gorgan, IranDepartment of Biology, Faculty of Science, Golestan University, Gorgan, IranThe classical renin-angiotensin system (RAS) has an important role in the cardiovascular system and water homeostasis in the body. Recently, the existence of RAS with all of its components has been shown in the mammalian brain. RAS participates in many brain activities, including memory acquisition and consolidation. Since the cholinergic neurotransmission in the hippocampus is crucial for these functions, this study aims to evaluate the hippocampal angiotensin receptors (ATs) and choline acetyltransferase (ChAT) mRNA in the renovascular hypertensive rats in captopril- and losartan-treated hypertensive rats.https://doi.org/10.1515/tnsci-2022-0215goldblatt hypertensionat receptorshippocampuschat |
| spellingShingle | Sepehri Hamid Ganji Farzaneh Nazari Zahra Vahid Marzieh Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system Translational Neuroscience goldblatt hypertension at receptors hippocampus chat |
| title | Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system |
| title_full | Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system |
| title_fullStr | Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system |
| title_full_unstemmed | Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system |
| title_short | Effects of Goldblatt hypertension on rats’ hippocampal cholinergic system |
| title_sort | effects of goldblatt hypertension on rats hippocampal cholinergic system |
| topic | goldblatt hypertension at receptors hippocampus chat |
| url | https://doi.org/10.1515/tnsci-2022-0215 |
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