Plasma proteome profiling identifies changes associated to AD but not to FTD

Plasma proteome profiling identifies changes associated to AD but not to FTD

Abstract Background Frontotemporal dementia (FTD) is caused by frontotemporal lobar degeneration (FTLD), characterized mainly by inclusions of Tau (FTLD-Tau) or TAR DNA binding43 (FTLD-TDP) proteins. Plasma biomarkers are strongly needed for specific diagnosis and potential treatment monitoring of F...

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Main Authors: R. Babapour Mofrad, M. del Campo, C. F. W. Peeters, L. H. H. Meeter, H. Seelaar, M. Koel-Simmelink, I. H. G. B. Ramakers, H. A. M. Middelkoop, P. P. De Deyn, J. A. H. R. Claassen, J. C. van Swieten, C. Bridel, J. J. M. Hoozemans, P. Scheltens, W. M. van der Flier, Y. A. L. Pijnenburg, Charlotte E. Teunissen
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Acta Neuropathologica Communications
Subjects:
Plasma biomarkers
Frontotemporal dementia
FTD
Alzheimer’s disease
AD
Somascan
Online Access:https://doi.org/10.1186/s40478-022-01458-w

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