Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model.

Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model.

The need for new options for chronic lung diseases promotes the research on stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can modulate lung inflammation, but the data on cellular processes involved in early airway remodeling and the potential involvement of neuropepti...

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Bibliographic Details
Main Authors: Konrad Urbanek, Antonella De Angelis, Giuseppe Spaziano, Elena Piegari, Maria Matteis, Donato Cappetta, Grazia Esposito, Rosa Russo, Gioia Tartaglione, Raffaele De Palma, Francesco Rossi, Bruno D'Agostino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4951036?pdf=render

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http://europepmc.org/articles/PMC4951036?pdf=render

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