Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy
Platinum-based anticancer drugs are widely used in the chemotherapy of human neoplasms. The major obstacle for the clinical use of this class of drugs is the development of resistance and toxicity. It is therefore very important to understand the chemical properties, transport and metabolic pathways...
Main Author: | Makovec Tomaz |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2019-03-01
|
Series: | Radiology and Oncology |
Subjects: | |
Online Access: | https://doi.org/10.2478/raon-2019-0018 |
Similar Items
-
Molecular mechanisms of cisplatin resistance in cervical cancer
by: Zhu H, et al.
Published: (2016-06-01) -
Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy
by: Tchounwou PB, et al.
Published: (2021-03-01) -
Cisplatin Induced Nephrotoxicity
by: Seyed Seifollah Beladi Mousavi, et al.
Published: (2014-02-01) -
ATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma
by: Zhang B, et al.
Published: (2019-01-01) -
Thromboembolic events in cancer patients on active treatment with cisplatin-based chemotherapy: another look!
by: Hikmat Abdel-Razeq, et al.
Published: (2018-03-01)