ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD
Objective: To determine association between iron deficiency anemia and bone profile in cases of chronic kidney disease not undergoing dialysis. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Chemical Pathology and Endocrinology, Armed Forces Institu...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2021-08-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/4009 |
| _version_ | 1818737157452333056 |
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| author | Shamsa Kanwal Muhammad Aamir Khurram Mansoor Naveed Asif Muhammad Tanveer |
| author_facet | Shamsa Kanwal Muhammad Aamir Khurram Mansoor Naveed Asif Muhammad Tanveer |
| author_sort | Shamsa Kanwal |
| collection | DOAJ |
| description | Objective: To determine association between iron deficiency anemia and bone profile in cases of chronic kidney disease not undergoing dialysis.
Study Design: Comparative cross sectional study.
Place and Duration of Study: Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology in collaboration with department of Nephrology, Armed Forces Institute of Urology, Rawalpindi, from Sep 2018 to Oct 2019.
Methodology: A total of 300 chronic kidney disease patients who were not dependent on any kind of dialysis were included in our study. Chronic kidney disease was confirmed according to National Kidney Foundation/Kidney Disease Outcome Quality Initiative criteria. Hemoglobin, Mean corpuscular volume and ferritin levels were used to diagnose iron deficiency anemia. Association of Calcium, inorganic Phosphorous, Magnesium, Alkaline phosphatase and Parathyroid Hormone (PTH) was determined with iron deficiency anemia.
Results: Out of 300 patients studied 201 (67%) were females while 99 (33%) were males. Mean age of participants was 43.51 ± 5.652 years. Mean duration of chronic kidney disease was 4.36 ± 3.712 years. One hundred and forty one (47%) patients had no anemia while 159 (53%) had presence of iron deficiency anemia. After applying binary logistic regression analysis hypocalcemia, hypophosphatemia and hypomagnesemia were noted to have a statistically significant association with iron deficiency anemia in the target sample size.
Conclusion: This study revealed a high frequency of iron deficiency anemia in non-dialysis chronic kidney disease patients. Hypocalcemia, hypophosphatemia and hypomagnesemia were found having strong association with presence of iron deficiency anemia in non-dialysis dependent chronic kidney disease patients. |
| first_indexed | 2024-12-18T00:48:35Z |
| format | Article |
| id | doaj.art-0887a8526b864fc78654b8ae163ea948 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-12-18T00:48:35Z |
| publishDate | 2021-08-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-0887a8526b864fc78654b8ae163ea9482022-12-21T21:26:44ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422021-08-0171412040810.51253/pafmj.v71i4.40094009ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKDShamsa Kanwal0Muhammad Aamir1Khurram Mansoor2Naveed Asif3Muhammad Tanveer4Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Urology/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital Quetta/National University of Medical Sciences (NUMS) PakistanArmed Forces Institute of Urology/National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To determine association between iron deficiency anemia and bone profile in cases of chronic kidney disease not undergoing dialysis. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology in collaboration with department of Nephrology, Armed Forces Institute of Urology, Rawalpindi, from Sep 2018 to Oct 2019. Methodology: A total of 300 chronic kidney disease patients who were not dependent on any kind of dialysis were included in our study. Chronic kidney disease was confirmed according to National Kidney Foundation/Kidney Disease Outcome Quality Initiative criteria. Hemoglobin, Mean corpuscular volume and ferritin levels were used to diagnose iron deficiency anemia. Association of Calcium, inorganic Phosphorous, Magnesium, Alkaline phosphatase and Parathyroid Hormone (PTH) was determined with iron deficiency anemia. Results: Out of 300 patients studied 201 (67%) were females while 99 (33%) were males. Mean age of participants was 43.51 ± 5.652 years. Mean duration of chronic kidney disease was 4.36 ± 3.712 years. One hundred and forty one (47%) patients had no anemia while 159 (53%) had presence of iron deficiency anemia. After applying binary logistic regression analysis hypocalcemia, hypophosphatemia and hypomagnesemia were noted to have a statistically significant association with iron deficiency anemia in the target sample size. Conclusion: This study revealed a high frequency of iron deficiency anemia in non-dialysis chronic kidney disease patients. Hypocalcemia, hypophosphatemia and hypomagnesemia were found having strong association with presence of iron deficiency anemia in non-dialysis dependent chronic kidney disease patients.https://pafmj.org/index.php/PAFMJ/article/view/4009anemiabone profilechronic kidney disease |
| spellingShingle | Shamsa Kanwal Muhammad Aamir Khurram Mansoor Naveed Asif Muhammad Tanveer ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD Pakistan Armed Forces Medical Journal anemia bone profile chronic kidney disease |
| title | ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD |
| title_full | ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD |
| title_fullStr | ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD |
| title_full_unstemmed | ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD |
| title_short | ASSOCIATION BETWEEN ANEMIA AND BONE PROFILE IN NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE ANEMIA AND BONE PROFILE IN CKD |
| title_sort | association between anemia and bone profile in non dialysis dependent chronic kidney disease anemia and bone profile in ckd |
| topic | anemia bone profile chronic kidney disease |
| url | https://pafmj.org/index.php/PAFMJ/article/view/4009 |
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