High PI3K/mTOR and low MAPK/JNK activity results in decreased apoptosis and autophagy in nasal polyposis

High PI3K/mTOR and low MAPK/JNK activity results in decreased apoptosis and autophagy in nasal polyposis

Introduction: Nasal polyposis is a progressive inflammatory disease that reduces the quality of life. The role of apoptotic and autophagic pathways in nasal polyposis pathogenesis is not yet clearly known. Objective: In this study we aimed to investigate apoptotic (MAPK/JNK), anti-apoptotic (PI3K/mT...

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Bibliographic Details
Main Authors: Fatma Simsek, Erdem Eren, Selen Bahceci, Ibrahim Aladag
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Brazilian Journal of Otorhinolaryngology
Subjects:
Nasal polyp
Apoptosis
Autophagy
TUNEL
Eosinophil
Online Access:http://www.sciencedirect.com/science/article/pii/S1808869420300069

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