In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images
AIM: To investigate the aqueous vein in vivo by using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography angiography (OCTA). METHODS: In this cross-sectional comparative study, 30 healthy participants were enrolled. Images of the aqueous and conjunctival v...
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| Format: | Article |
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Press of International Journal of Ophthalmology (IJO PRESS)
2023-09-01
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| Series: | International Journal of Ophthalmology |
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| Online Access: | http://ies.ijo.cn/en_publish/2023/9/20230915.pdf |
| _version_ | 1797739523405250560 |
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| author | Zhi-Qi Chen Wei Chen Chao-Hua Deng Jing-Min Guo Hong Zhang Jun-Ming Wang |
| author_facet | Zhi-Qi Chen Wei Chen Chao-Hua Deng Jing-Min Guo Hong Zhang Jun-Ming Wang |
| author_sort | Zhi-Qi Chen |
| collection | DOAJ |
| description | AIM: To investigate the aqueous vein in vivo by using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography angiography (OCTA). METHODS: In this cross-sectional comparative study, 30 healthy participants were enrolled. Images of the aqueous and conjunctival veins were captured by EDI-OCT and OCTA before and after water loading. The area, height, width, location depth and blood flow of the aqueous vein and conjunctival vein were measured by Image J software. RESULTS: In the static state, the area of the aqueous vein was 8166.7±3272.7 μm2, which was smaller than that of the conjunctival vein (13 690±7457 μm2, P<0.001). The mean blood flow density of the aqueous vein was 35.3%±12.6%, which was significantly less than that of the conjunctival vein (51.5%±10.6%, P<0.001). After water loading, the area of the aqueous vein decreased significantly from 8725.8±779.4 μm2 (baseline) to 7005.2±566.2 μm2 at 45min but rose to 7863.0±703.2 μm2 at 60min (P=0.032). The blood flow density of the aqueous vein decreased significantly from 41.2%±4.5% (baseline) to 35.4%±3.2% at 30min but returned to 45.6%±3.6% at 60min (P=0.021). CONCLUSION: The structure and blood flow density of the aqueous vein can be effectively evaluated by OCT and OCTA. These may become biological indicators to evaluate aqueous vein changes and aqueous outflow resistance under different interventions in glaucoma patients. |
| first_indexed | 2024-03-12T13:59:22Z |
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| id | doaj.art-0890a64e25b948bab6a2a1db686184e3 |
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| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-03-12T13:59:22Z |
| publishDate | 2023-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-0890a64e25b948bab6a2a1db686184e32023-08-22T08:47:16ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982023-09-011691482148810.18240/ijo.2023.09.1520230915In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography imagesZhi-Qi Chen0Wei Chen1Chao-Hua Deng2Jing-Min Guo3Hong Zhang4Jun-Ming Wang5Jun-Ming Wang. Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei Province, China. eyedrwjm@163.comDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, ChinaDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, ChinaDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, ChinaDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, ChinaDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, ChinaAIM: To investigate the aqueous vein in vivo by using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography angiography (OCTA). METHODS: In this cross-sectional comparative study, 30 healthy participants were enrolled. Images of the aqueous and conjunctival veins were captured by EDI-OCT and OCTA before and after water loading. The area, height, width, location depth and blood flow of the aqueous vein and conjunctival vein were measured by Image J software. RESULTS: In the static state, the area of the aqueous vein was 8166.7±3272.7 μm2, which was smaller than that of the conjunctival vein (13 690±7457 μm2, P<0.001). The mean blood flow density of the aqueous vein was 35.3%±12.6%, which was significantly less than that of the conjunctival vein (51.5%±10.6%, P<0.001). After water loading, the area of the aqueous vein decreased significantly from 8725.8±779.4 μm2 (baseline) to 7005.2±566.2 μm2 at 45min but rose to 7863.0±703.2 μm2 at 60min (P=0.032). The blood flow density of the aqueous vein decreased significantly from 41.2%±4.5% (baseline) to 35.4%±3.2% at 30min but returned to 45.6%±3.6% at 60min (P=0.021). CONCLUSION: The structure and blood flow density of the aqueous vein can be effectively evaluated by OCT and OCTA. These may become biological indicators to evaluate aqueous vein changes and aqueous outflow resistance under different interventions in glaucoma patients.http://ies.ijo.cn/en_publish/2023/9/20230915.pdfaqueous veinoptical coherence tomographyoptical coherence tomography angiographywater drinking test |
| spellingShingle | Zhi-Qi Chen Wei Chen Chao-Hua Deng Jing-Min Guo Hong Zhang Jun-Ming Wang In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images International Journal of Ophthalmology aqueous vein optical coherence tomography optical coherence tomography angiography water drinking test |
| title | In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| title_full | In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| title_fullStr | In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| title_full_unstemmed | In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| title_short | In vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| title_sort | in vivo quantification of human aqueous veins by enhanced depth imaging optical coherence tomography and optical coherence tomography angiography images |
| topic | aqueous vein optical coherence tomography optical coherence tomography angiography water drinking test |
| url | http://ies.ijo.cn/en_publish/2023/9/20230915.pdf |
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