Epstein-Barr virus nuclear antigen 3C (EBNA3C) interacts with the metabolism sensing C-terminal binding protein (CtBP) repressor to upregulate host genes.

Epstein-Barr virus nuclear antigen 3C (EBNA3C) interacts with the metabolism sensing C-terminal binding protein (CtBP) repressor to upregulate host genes.

Epstein-Barr virus (EBV) infection is associated with the development of specific types of lymphoma and some epithelial cancers. EBV infection of resting B-lymphocytes in vitro drives them to proliferate as lymphoblastoid cell lines (LCLs) and serves as a model for studying EBV lymphomagenesis. EBV...

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Bibliographic Details
Main Authors:	Makoto Ohashi, Mitchell Hayes, Kyle McChesney, Eric Johannsen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-03-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1009419

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