Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy
Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the inability to monitor dynamic drug level changes. I...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/13/7/726 |
| _version_ | 1827733651680395264 |
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| author | Yuqiao Liu Junmin Li Shenghao Xiao Yanhui Liu Mingxia Bai Lixiu Gong Jiaqian Zhao Dajing Chen |
| author_facet | Yuqiao Liu Junmin Li Shenghao Xiao Yanhui Liu Mingxia Bai Lixiu Gong Jiaqian Zhao Dajing Chen |
| author_sort | Yuqiao Liu |
| collection | DOAJ |
| description | Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the inability to monitor dynamic drug level changes. In recent years, wearable sensors have emerged as a promising solution for drug monitoring. These sensors offer real-time and continuous measurement of drug concentrations in biofluids, enabling personalized medicine and reducing the risk of toxicity. This review provides an overview of drugs detectable by wearable sensors and explores biosensing technologies that can enable drug monitoring in the future. It presents a comparative analysis of multiple biosensing technologies and evaluates their strengths and limitations for integration into wearable detection systems. The promising capabilities of wearable sensors for real-time and continuous drug monitoring offer revolutionary advancements in diagnostic tools, supporting personalized medicine and optimal therapeutic effects. Wearable sensors are poised to become essential components of healthcare systems, catering to the diverse needs of patients and reducing healthcare costs. |
| first_indexed | 2024-03-11T01:15:11Z |
| format | Article |
| id | doaj.art-0894b8686d574932bfb2a054a5cc833e |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T01:15:11Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-0894b8686d574932bfb2a054a5cc833e2023-11-18T18:33:08ZengMDPI AGBiosensors2079-63742023-07-0113772610.3390/bios13070726Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized TherapyYuqiao Liu0Junmin Li1Shenghao Xiao2Yanhui Liu3Mingxia Bai4Lixiu Gong5Jiaqian Zhao6Dajing Chen7School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, ChinaPrecision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the inability to monitor dynamic drug level changes. In recent years, wearable sensors have emerged as a promising solution for drug monitoring. These sensors offer real-time and continuous measurement of drug concentrations in biofluids, enabling personalized medicine and reducing the risk of toxicity. This review provides an overview of drugs detectable by wearable sensors and explores biosensing technologies that can enable drug monitoring in the future. It presents a comparative analysis of multiple biosensing technologies and evaluates their strengths and limitations for integration into wearable detection systems. The promising capabilities of wearable sensors for real-time and continuous drug monitoring offer revolutionary advancements in diagnostic tools, supporting personalized medicine and optimal therapeutic effects. Wearable sensors are poised to become essential components of healthcare systems, catering to the diverse needs of patients and reducing healthcare costs.https://www.mdpi.com/2079-6374/13/7/726wearable sensorsdrug analysispersonalized medicinetherapeutic drug monitoring |
| spellingShingle | Yuqiao Liu Junmin Li Shenghao Xiao Yanhui Liu Mingxia Bai Lixiu Gong Jiaqian Zhao Dajing Chen Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy Biosensors wearable sensors drug analysis personalized medicine therapeutic drug monitoring |
| title | Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy |
| title_full | Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy |
| title_fullStr | Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy |
| title_full_unstemmed | Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy |
| title_short | Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy |
| title_sort | revolutionizing precision medicine exploring wearable sensors for therapeutic drug monitoring and personalized therapy |
| topic | wearable sensors drug analysis personalized medicine therapeutic drug monitoring |
| url | https://www.mdpi.com/2079-6374/13/7/726 |
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