A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1
Abstract In the therapeutic management of eosinophilic disorder, it is important to prevent hypereosinophilia (HE)‐related organ damage even in the process of diagnosis. We describe here a unique clinical and histopathological findings of the patient with HE accompanied with digital ischaemia. Treat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Series: | Skin Health and Disease |
| Online Access: | https://doi.org/10.1002/ski2.32 |
| _version_ | 1811185512165146624 |
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| author | M. Kaga H. Takeuchi K. Iwahara H. Ihara |
| author_facet | M. Kaga H. Takeuchi K. Iwahara H. Ihara |
| author_sort | M. Kaga |
| collection | DOAJ |
| description | Abstract In the therapeutic management of eosinophilic disorder, it is important to prevent hypereosinophilia (HE)‐related organ damage even in the process of diagnosis. We describe here a unique clinical and histopathological findings of the patient with HE accompanied with digital ischaemia. Treatment with intravenous prostaglandin E1 was essential for digital ischaemia in our case while benralizumab, humanized monoclonal antibody against interleukin‐5 receptorα, did not affect. Our case suggests an earlier intervention for digital ischaemia in the therapeutic management of eosiniphilic disorder. |
| first_indexed | 2024-04-11T13:30:40Z |
| format | Article |
| id | doaj.art-0894e4facfd44333bb7666dfd6d5b7bf |
| institution | Directory Open Access Journal |
| issn | 2690-442X |
| language | English |
| last_indexed | 2024-04-11T13:30:40Z |
| publishDate | 2021-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Skin Health and Disease |
| spelling | doaj.art-0894e4facfd44333bb7666dfd6d5b7bf2022-12-22T04:21:49ZengWileySkin Health and Disease2690-442X2021-06-0112n/an/a10.1002/ski2.32A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1M. Kaga0H. Takeuchi1K. Iwahara2H. Ihara3Division of Dermatology Koto Hospital Tokyo JapanDivision of Dermatology Koto Hospital Tokyo JapanDivision of Dermatology Koto Hospital Tokyo JapanDivision of Respiratory Medicine Koto Hospital Tokyo JapanAbstract In the therapeutic management of eosinophilic disorder, it is important to prevent hypereosinophilia (HE)‐related organ damage even in the process of diagnosis. We describe here a unique clinical and histopathological findings of the patient with HE accompanied with digital ischaemia. Treatment with intravenous prostaglandin E1 was essential for digital ischaemia in our case while benralizumab, humanized monoclonal antibody against interleukin‐5 receptorα, did not affect. Our case suggests an earlier intervention for digital ischaemia in the therapeutic management of eosiniphilic disorder.https://doi.org/10.1002/ski2.32 |
| spellingShingle | M. Kaga H. Takeuchi K. Iwahara H. Ihara A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 Skin Health and Disease |
| title | A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 |
| title_full | A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 |
| title_fullStr | A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 |
| title_full_unstemmed | A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 |
| title_short | A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 |
| title_sort | case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin e1 |
| url | https://doi.org/10.1002/ski2.32 |
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