The role of extracellular vesicles in COPD and potential clinical value
Abstract Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure that are secreted by various cells. They contain a variety of bioactive substances, w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12931-024-02719-z |
| _version_ | 1827326422692134912 |
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| author | Shasha Liu Xiaowu Tan Sha Liu |
| author_facet | Shasha Liu Xiaowu Tan Sha Liu |
| author_sort | Shasha Liu |
| collection | DOAJ |
| description | Abstract Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure that are secreted by various cells. They contain a variety of bioactive substances, which can regulate various physiological and pathological processes and are closely related to the development of diseases. Recently, EVs have emerged as a novel tool for intercellular crosstalk, which plays an essential role in COPD development. This paper reviews the role of EVs in the development of COPD and their potential clinical value, in order to provide a reference for further research on COPD. |
| first_indexed | 2024-03-07T14:44:17Z |
| format | Article |
| id | doaj.art-0897377fc4cc4742b6222a2cbfc3618e |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-03-07T14:44:17Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-0897377fc4cc4742b6222a2cbfc3618e2024-03-05T20:02:30ZengBMCRespiratory Research1465-993X2024-02-0125111010.1186/s12931-024-02719-zThe role of extracellular vesicles in COPD and potential clinical valueShasha Liu0Xiaowu Tan1Sha Liu2Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital, Hengyang Medical School, University of South ChinaDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital, Hengyang Medical School, University of South ChinaDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital, Hengyang Medical School, University of South ChinaAbstract Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure that are secreted by various cells. They contain a variety of bioactive substances, which can regulate various physiological and pathological processes and are closely related to the development of diseases. Recently, EVs have emerged as a novel tool for intercellular crosstalk, which plays an essential role in COPD development. This paper reviews the role of EVs in the development of COPD and their potential clinical value, in order to provide a reference for further research on COPD.https://doi.org/10.1186/s12931-024-02719-zExtracellular vesiclesChronic obstructive pulmonary diseasePathogenesisBiomarkersClinical application |
| spellingShingle | Shasha Liu Xiaowu Tan Sha Liu The role of extracellular vesicles in COPD and potential clinical value Respiratory Research Extracellular vesicles Chronic obstructive pulmonary disease Pathogenesis Biomarkers Clinical application |
| title | The role of extracellular vesicles in COPD and potential clinical value |
| title_full | The role of extracellular vesicles in COPD and potential clinical value |
| title_fullStr | The role of extracellular vesicles in COPD and potential clinical value |
| title_full_unstemmed | The role of extracellular vesicles in COPD and potential clinical value |
| title_short | The role of extracellular vesicles in COPD and potential clinical value |
| title_sort | role of extracellular vesicles in copd and potential clinical value |
| topic | Extracellular vesicles Chronic obstructive pulmonary disease Pathogenesis Biomarkers Clinical application |
| url | https://doi.org/10.1186/s12931-024-02719-z |
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