Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>)
Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing the viruses carried by pangolins is a logical approach to evaluate the range of potential pathogens and help with conservation. This study provides insight into viral communities of Malayan Pangolins (<i>...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-10-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/11/11/979 |
| _version_ | 1819147952023666688 |
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| author | Ping Liu Wu Chen Jin-Ping Chen |
| author_facet | Ping Liu Wu Chen Jin-Ping Chen |
| author_sort | Ping Liu |
| collection | DOAJ |
| description | Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing the viruses carried by pangolins is a logical approach to evaluate the range of potential pathogens and help with conservation. This study provides insight into viral communities of Malayan Pangolins (<i>Manis javanica</i>) as well as the molecular epidemiology of dominant pathogenic viruses between Malayan Pangolin and other hosts. A total of 62,508 <i>de novo</i> assembled contigs were constructed, and a BLAST search revealed 3600 ones (≥300 nt) were related to viral sequences, of which 68 contigs had a high level of sequence similarity to known viruses, while dominant viruses were the Sendai virus and Coronavirus. This is the first report on the viral diversity of pangolins, expanding our understanding of the virome in endangered species, and providing insight into the overall diversity of viruses that may be capable of directly or indirectly crossing over into other mammals. |
| first_indexed | 2024-12-22T13:37:59Z |
| format | Article |
| id | doaj.art-089a62ce618e4fb8aa79e59db551b4eb |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-12-22T13:37:59Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-089a62ce618e4fb8aa79e59db551b4eb2022-12-21T18:24:00ZengMDPI AGViruses1999-49152019-10-01111197910.3390/v11110979v11110979Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>)Ping Liu0Wu Chen1Jin-Ping Chen2Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510260, ChinaGuangzhou Zoo, Guangzhou 510230, ChinaGuangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510260, ChinaPangolins are endangered animals in urgent need of protection. Identifying and cataloguing the viruses carried by pangolins is a logical approach to evaluate the range of potential pathogens and help with conservation. This study provides insight into viral communities of Malayan Pangolins (<i>Manis javanica</i>) as well as the molecular epidemiology of dominant pathogenic viruses between Malayan Pangolin and other hosts. A total of 62,508 <i>de novo</i> assembled contigs were constructed, and a BLAST search revealed 3600 ones (≥300 nt) were related to viral sequences, of which 68 contigs had a high level of sequence similarity to known viruses, while dominant viruses were the Sendai virus and Coronavirus. This is the first report on the viral diversity of pangolins, expanding our understanding of the virome in endangered species, and providing insight into the overall diversity of viruses that may be capable of directly or indirectly crossing over into other mammals.https://www.mdpi.com/1999-4915/11/11/979virome<i>manis javanica</i>sendai viruscoronavirusmolecular epidemiology |
| spellingShingle | Ping Liu Wu Chen Jin-Ping Chen Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) Viruses virome <i>manis javanica</i> sendai virus coronavirus molecular epidemiology |
| title | Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) |
| title_full | Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) |
| title_fullStr | Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) |
| title_full_unstemmed | Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) |
| title_short | Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (<i>Manis javanica</i>) |
| title_sort | viral metagenomics revealed sendai virus and coronavirus infection of malayan pangolins i manis javanica i |
| topic | virome <i>manis javanica</i> sendai virus coronavirus molecular epidemiology |
| url | https://www.mdpi.com/1999-4915/11/11/979 |
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