Health Benefits of Nut Consumption in Middle-Aged and Elderly Population

Aging is considered the major risk factor for most chronic disorders. Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading...

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Main Authors: Marius Emil Rusu, Andrei Mocan, Isabel C. F. R. Ferreira, Daniela-Saveta Popa
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/8/8/302
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author Marius Emil Rusu
Andrei Mocan
Isabel C. F. R. Ferreira
Daniela-Saveta Popa
author_facet Marius Emil Rusu
Andrei Mocan
Isabel C. F. R. Ferreira
Daniela-Saveta Popa
author_sort Marius Emil Rusu
collection DOAJ
description Aging is considered the major risk factor for most chronic disorders. Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading in time to age-related diseases. This review investigated the most recent clinical trials and cohort studies published in the last ten years, which presented the influence of tree nut and peanut antioxidant diets in preventing or delaying age-related diseases in middle-aged and elderly subjects (≥55 years old). Tree nut and peanut ingestion has the possibility to influence blood lipid count, biochemical and anthropometric parameters, endothelial function and inflammatory biomarkers, thereby positively affecting cardiometabolic morbidity and mortality, cancers, and cognitive disorders, mainly through the nuts’ healthy lipid profile and antioxidant and anti-inflammatory mechanisms of actions. Clinical evidence and scientific findings demonstrate the importance of diets characterized by a high intake of nuts and emphasize their potential in preventing age-related diseases, validating the addition of tree nuts and peanuts in the diet of older adults. Therefore, increased consumption of bioactive antioxidant compounds from nuts clearly impacts many risk factors related to aging and can extend health span and lifespan.
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spelling doaj.art-089a69dab0784ed9b03213e604ad3b672023-08-02T04:57:36ZengMDPI AGAntioxidants2076-39212019-08-018830210.3390/antiox8080302antiox8080302Health Benefits of Nut Consumption in Middle-Aged and Elderly PopulationMarius Emil Rusu0Andrei Mocan1Isabel C. F. R. Ferreira2Daniela-Saveta Popa3Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaDepartment of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança (IPB), Campus de Santa Apolónia, 5300-253 Bragança, PortugalDepartment of Toxicology, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, 8 Victor Babes, 400012 Cluj-Napoca, RomaniaAging is considered the major risk factor for most chronic disorders. Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading in time to age-related diseases. This review investigated the most recent clinical trials and cohort studies published in the last ten years, which presented the influence of tree nut and peanut antioxidant diets in preventing or delaying age-related diseases in middle-aged and elderly subjects (≥55 years old). Tree nut and peanut ingestion has the possibility to influence blood lipid count, biochemical and anthropometric parameters, endothelial function and inflammatory biomarkers, thereby positively affecting cardiometabolic morbidity and mortality, cancers, and cognitive disorders, mainly through the nuts’ healthy lipid profile and antioxidant and anti-inflammatory mechanisms of actions. Clinical evidence and scientific findings demonstrate the importance of diets characterized by a high intake of nuts and emphasize their potential in preventing age-related diseases, validating the addition of tree nuts and peanuts in the diet of older adults. Therefore, increased consumption of bioactive antioxidant compounds from nuts clearly impacts many risk factors related to aging and can extend health span and lifespan.https://www.mdpi.com/2076-3921/8/8/302tree nutspeanutsmiddle-aged populationantioxidantsage-related diseaseselderlynut-enriched Mediterranean dietinflammationoxidative stress
spellingShingle Marius Emil Rusu
Andrei Mocan
Isabel C. F. R. Ferreira
Daniela-Saveta Popa
Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
Antioxidants
tree nuts
peanuts
middle-aged population
antioxidants
age-related diseases
elderly
nut-enriched Mediterranean diet
inflammation
oxidative stress
title Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
title_full Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
title_fullStr Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
title_full_unstemmed Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
title_short Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
title_sort health benefits of nut consumption in middle aged and elderly population
topic tree nuts
peanuts
middle-aged population
antioxidants
age-related diseases
elderly
nut-enriched Mediterranean diet
inflammation
oxidative stress
url https://www.mdpi.com/2076-3921/8/8/302
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