Circadian cycle and neuroinflammation

Circadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of...

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Main Authors: Xu Xinzi, Wang Junli, Chen Guohua
Format: Article
Language:English
Published: De Gruyter 2023-10-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-0712
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author Xu Xinzi
Wang Junli
Chen Guohua
author_facet Xu Xinzi
Wang Junli
Chen Guohua
author_sort Xu Xinzi
collection DOAJ
description Circadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of neuroinflammation by inducing glial cell activation and peripheral immune responses. In this article, we briefly described the research progress of neuroinflammation and circadian rhythm in recent years and explored the effects and possible mechanism of circadian rhythmicity on microglia, astrocytes, and peripheral immune function.
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spelling doaj.art-089bbaf91ee04b048f67c05f97ca188a2023-10-23T07:49:54ZengDe GruyterOpen Life Sciences2391-54122023-10-011815647910.1515/biol-2022-0712Circadian cycle and neuroinflammationXu Xinzi0Wang Junli1Chen Guohua2College of Clinical Chinese Medicine, Hubei University of Chinese Medicine, Wuhan430065, ChinaDepartment of Neurology, Wuhan No. 1 Hospital, Wuhan430022, ChinaDepartment of Neurology, Wuhan No. 1 Hospital, Wuhan430022, ChinaCircadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of neuroinflammation by inducing glial cell activation and peripheral immune responses. In this article, we briefly described the research progress of neuroinflammation and circadian rhythm in recent years and explored the effects and possible mechanism of circadian rhythmicity on microglia, astrocytes, and peripheral immune function.https://doi.org/10.1515/biol-2022-0712circadian rhythmneuroinflammationmicrogliaastrocyte
spellingShingle Xu Xinzi
Wang Junli
Chen Guohua
Circadian cycle and neuroinflammation
Open Life Sciences
circadian rhythm
neuroinflammation
microglia
astrocyte
title Circadian cycle and neuroinflammation
title_full Circadian cycle and neuroinflammation
title_fullStr Circadian cycle and neuroinflammation
title_full_unstemmed Circadian cycle and neuroinflammation
title_short Circadian cycle and neuroinflammation
title_sort circadian cycle and neuroinflammation
topic circadian rhythm
neuroinflammation
microglia
astrocyte
url https://doi.org/10.1515/biol-2022-0712
work_keys_str_mv AT xuxinzi circadiancycleandneuroinflammation
AT wangjunli circadiancycleandneuroinflammation
AT chenguohua circadiancycleandneuroinflammation