Circadian cycle and neuroinflammation
Circadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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De Gruyter
2023-10-01
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Series: | Open Life Sciences |
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Online Access: | https://doi.org/10.1515/biol-2022-0712 |
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author | Xu Xinzi Wang Junli Chen Guohua |
author_facet | Xu Xinzi Wang Junli Chen Guohua |
author_sort | Xu Xinzi |
collection | DOAJ |
description | Circadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of neuroinflammation by inducing glial cell activation and peripheral immune responses. In this article, we briefly described the research progress of neuroinflammation and circadian rhythm in recent years and explored the effects and possible mechanism of circadian rhythmicity on microglia, astrocytes, and peripheral immune function. |
first_indexed | 2024-03-11T16:42:58Z |
format | Article |
id | doaj.art-089bbaf91ee04b048f67c05f97ca188a |
institution | Directory Open Access Journal |
issn | 2391-5412 |
language | English |
last_indexed | 2024-03-11T16:42:58Z |
publishDate | 2023-10-01 |
publisher | De Gruyter |
record_format | Article |
series | Open Life Sciences |
spelling | doaj.art-089bbaf91ee04b048f67c05f97ca188a2023-10-23T07:49:54ZengDe GruyterOpen Life Sciences2391-54122023-10-011815647910.1515/biol-2022-0712Circadian cycle and neuroinflammationXu Xinzi0Wang Junli1Chen Guohua2College of Clinical Chinese Medicine, Hubei University of Chinese Medicine, Wuhan430065, ChinaDepartment of Neurology, Wuhan No. 1 Hospital, Wuhan430022, ChinaDepartment of Neurology, Wuhan No. 1 Hospital, Wuhan430022, ChinaCircadian cycle is a fundamental characteristic of life formed in the long-term evolution of organisms and plays an important role in maintaining the proliferation, migration, and activation of immune cells. Studies have shown that circadian rhythm disorders affect the occurrence and development of neuroinflammation by inducing glial cell activation and peripheral immune responses. In this article, we briefly described the research progress of neuroinflammation and circadian rhythm in recent years and explored the effects and possible mechanism of circadian rhythmicity on microglia, astrocytes, and peripheral immune function.https://doi.org/10.1515/biol-2022-0712circadian rhythmneuroinflammationmicrogliaastrocyte |
spellingShingle | Xu Xinzi Wang Junli Chen Guohua Circadian cycle and neuroinflammation Open Life Sciences circadian rhythm neuroinflammation microglia astrocyte |
title | Circadian cycle and neuroinflammation |
title_full | Circadian cycle and neuroinflammation |
title_fullStr | Circadian cycle and neuroinflammation |
title_full_unstemmed | Circadian cycle and neuroinflammation |
title_short | Circadian cycle and neuroinflammation |
title_sort | circadian cycle and neuroinflammation |
topic | circadian rhythm neuroinflammation microglia astrocyte |
url | https://doi.org/10.1515/biol-2022-0712 |
work_keys_str_mv | AT xuxinzi circadiancycleandneuroinflammation AT wangjunli circadiancycleandneuroinflammation AT chenguohua circadiancycleandneuroinflammation |