Inferring the Clonal Structure of Viral Populations from Time Series Sequencing.

RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We would like to identify the underlying evolutionary structures....

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Bibliographic Details
Main Authors: Donatien F Chedom, Pablo R Murcia, Chris D Greenman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4646700?pdf=render

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