Inferring the Clonal Structure of Viral Populations from Time Series Sequencing.
RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We would like to identify the underlying evolutionary structures....
Main Authors: | Donatien F Chedom, Pablo R Murcia, Chris D Greenman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4646700?pdf=render |
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