Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats

Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats

<p>Abstract</p> <p>Background</p> <p>11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and its inhibition ameliorates obesity and metabolic syndrome. So far, no studies have reported the eff...

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Bibliographic Details
Main Authors: Ayyalasomayajula Vajreswari, Veettil Giridharan, Ananthathmakula Prashanth, Sakamuri Vara Prasad SS
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Nutrition Journal
Online Access:http://www.nutritionj.com/content/10/1/70

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