The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study
(1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment an...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
|
| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/11/8/1013 |
| _version_ | 1797524484640473088 |
|---|---|
| author | Paulina Beata Golińska Artur Józef Sawicki Łucja Bieleninik Mariola Bidzan |
| author_facet | Paulina Beata Golińska Artur Józef Sawicki Łucja Bieleninik Mariola Bidzan |
| author_sort | Paulina Beata Golińska |
| collection | DOAJ |
| description | (1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment and study procedures; (2) Methods: From 45 participants recruited, 39 were allocated (mean age 65.31; 43.59% men) to PD-NC, PD-MCI and CG (13 per group). To assess attention, we used three tasks from the ROtman–Baycrest Battery for Investigating Attention: Simple Reaction time (RT), Choice RT, and Prepare RT. We conducted a mixed-model analysis of variance with a 3 (groups) × 4 (tasks) design to compare reaction times; (3) Results: PD-MCI had slower reaction times than PD-NC (<i>p</i> = 0.028) and the CG (<i>p</i> = 0.052); there was no difference between PD-NC and CG. PD-MCI might perform worse on monitoring tasks than PD-NC, <i>Z</i> = −1.68, <i>p</i> = 0.092. Nearly half the volunteers from the CG and 87% of all eligible patients were enrolled in the study and completed all neuropsychological procedures; (4) Conclusions: General cognitive decline appears related to partial deficits in energization and tends to impair attentional monitoring. Furthermore, PD-NC exhibited similar reaction times to the CG. Results from the feasibility study contributed to the definitive study. |
| first_indexed | 2024-03-10T08:58:05Z |
| format | Article |
| id | doaj.art-08a70c25d316433387f4780f8cd5ea35 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T08:58:05Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-08a70c25d316433387f4780f8cd5ea352023-11-22T06:58:45ZengMDPI AGBrain Sciences2076-34252021-07-01118101310.3390/brainsci11081013The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility StudyPaulina Beata Golińska0Artur Józef Sawicki1Łucja Bieleninik2Mariola Bidzan3Institute of Psychology, University of Gdańsk, 80-309 Gdańsk, PolandInstitute of Psychology, University of Gdańsk, 80-309 Gdańsk, PolandInstitute of Psychology, University of Gdańsk, 80-309 Gdańsk, PolandInstitute of Psychology, University of Gdańsk, 80-309 Gdańsk, Poland(1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment and study procedures; (2) Methods: From 45 participants recruited, 39 were allocated (mean age 65.31; 43.59% men) to PD-NC, PD-MCI and CG (13 per group). To assess attention, we used three tasks from the ROtman–Baycrest Battery for Investigating Attention: Simple Reaction time (RT), Choice RT, and Prepare RT. We conducted a mixed-model analysis of variance with a 3 (groups) × 4 (tasks) design to compare reaction times; (3) Results: PD-MCI had slower reaction times than PD-NC (<i>p</i> = 0.028) and the CG (<i>p</i> = 0.052); there was no difference between PD-NC and CG. PD-MCI might perform worse on monitoring tasks than PD-NC, <i>Z</i> = −1.68, <i>p</i> = 0.092. Nearly half the volunteers from the CG and 87% of all eligible patients were enrolled in the study and completed all neuropsychological procedures; (4) Conclusions: General cognitive decline appears related to partial deficits in energization and tends to impair attentional monitoring. Furthermore, PD-NC exhibited similar reaction times to the CG. Results from the feasibility study contributed to the definitive study.https://www.mdpi.com/2076-3425/11/8/1013reaction timeexecutive functionsattentionneurodegenerative disorder |
| spellingShingle | Paulina Beata Golińska Artur Józef Sawicki Łucja Bieleninik Mariola Bidzan The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study Brain Sciences reaction time executive functions attention neurodegenerative disorder |
| title | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
| title_full | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
| title_fullStr | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
| title_full_unstemmed | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
| title_short | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
| title_sort | anterior attentional intentional system in patients with parkinson s disease a pilot and feasibility study |
| topic | reaction time executive functions attention neurodegenerative disorder |
| url | https://www.mdpi.com/2076-3425/11/8/1013 |
| work_keys_str_mv | AT paulinabeatagolinska theanteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT arturjozefsawicki theanteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT łucjabieleninik theanteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT mariolabidzan theanteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT paulinabeatagolinska anteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT arturjozefsawicki anteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT łucjabieleninik anteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy AT mariolabidzan anteriorattentionalintentionalsysteminpatientswithparkinsonsdiseaseapilotandfeasibilitystudy |