Chitinase-3-like Protein 1 Is Associated with Poor Virologic Control and Immune Activation in Children Living with HIV

Chitinase-3-like Protein 1 Is Associated with Poor Virologic Control and Immune Activation in Children Living with HIV

Perinatally infected children living with HIV (CLWH) face lifelong infection and associated inflammatory injury. Chitinase-like 3 protein-1 (CHI3L1) is expressed by activated neutrophils and may be a clinically informative marker of systemic inflammation in CLWH. We conducted a multi-centre, cross-s...

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Bibliographic Details
Main Authors: Isabelle Bernard, Doris G. Ransy, Jason Brophy, Fatima Kakkar, Ari Bitnun, Lindy Samson, Stanley Read, Hugo Soudeyns, Michael T. Hawkes, EPIC<sup>4</sup> Study Group
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
child
HIV
chitinase-3-like protein 1
inflammation
neutrophil
microbial translocation
Online Access:https://www.mdpi.com/1999-4915/14/12/2602

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