Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture
An accurate gas chromatography coupled to a flame ionization detector (GC-FID) method was validated for the simultaneous analysis of light hydrocarbons (C2-C4) in their gas mixture. The validation parameters were evaluated based on the ISO/IEC 17025 definition including method selectivity, repeatabi...
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
2016-09-01
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| Series: | Revista Colombiana de Química |
| Subjects: | |
| Online Access: | http://revistas.unal.edu.co/index.php/rcolquim/article/view/58085 |
| _version_ | 1818480261519638528 |
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| author | Oman Zuas Harry budiman Muhammad Rizky Mulyana |
| author_facet | Oman Zuas Harry budiman Muhammad Rizky Mulyana |
| author_sort | Oman Zuas |
| collection | DOAJ |
| description | An accurate gas chromatography coupled to a flame ionization detector (GC-FID) method was validated for the simultaneous analysis of light hydrocarbons (C2-C4) in their gas mixture. The validation parameters were evaluated based on the ISO/IEC 17025 definition including method selectivity, repeatability, accuracy, linearity, limit of detection (LOD), limit of quantitation (LOQ), and ruggedness. Under the optimum analytical conditions, the analysis of gas mixture revealed that each target component was well-separated with high selectivity property. The method was also found to be precise and accurate. The method linearity was found to be high with good correlation coefficient values (R2 ≥ 0.999) for all target components. It can be concluded that the GC-FID developed method is reliable and suitable for determination of light C2-C4 hydrocarbons (including ethylene, propane, propylene, isobutane, and n-butane) in their gas mixture. The validated method has successfully been applied to the estimation of hydrocarbons light C2-C4 hydrocarbons in natural gas samples, showing high performance repeatability with relative standard deviation (RSD) less than 1.0% and good selectivity with no interference from other possible components could be observed. |
| first_indexed | 2024-12-10T11:21:04Z |
| format | Article |
| id | doaj.art-08a7b77a7e0d4684bd2d43c2c9c3e2bc |
| institution | Directory Open Access Journal |
| issn | 0120-2804 2357-3791 |
| language | English |
| last_indexed | 2024-12-10T11:21:04Z |
| publishDate | 2016-09-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista Colombiana de Química |
| spelling | doaj.art-08a7b77a7e0d4684bd2d43c2c9c3e2bc2022-12-22T01:50:55ZengUniversidad Nacional de ColombiaRevista Colombiana de Química0120-28042357-37912016-09-01453222710.15446/rev.colomb.quim.v45n3.5808544220Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixtureOman Zuas0Harry budiman1Muhammad Rizky Mulyana2Gas Analysis Laboratory, Metrology in Chemistry Research Group, Research Centre for Chemistry, Indonesia Institute of Sciences (Puslit Kimia LIPI), Kawasan PUSPIPTEK Serpong 15314, Tangerang, Banten, Indonesia.Gas Analysis Laboratory, Metrology in Chemistry Research Group, Research Centre for Chemistry, Indonesia Institute of Sciences (Puslit Kimia LIPI), Kawasan PUSPIPTEK Serpong 15314, Tangerang, Banten, Indonesia.Gas Analysis Laboratory, Metrology in Chemistry Research Group, Research Centre for Chemistry, Indonesia Institute of Sciences (Puslit Kimia LIPI), Kawasan PUSPIPTEK Serpong 15314, Tangerang, Banten, Indonesia.An accurate gas chromatography coupled to a flame ionization detector (GC-FID) method was validated for the simultaneous analysis of light hydrocarbons (C2-C4) in their gas mixture. The validation parameters were evaluated based on the ISO/IEC 17025 definition including method selectivity, repeatability, accuracy, linearity, limit of detection (LOD), limit of quantitation (LOQ), and ruggedness. Under the optimum analytical conditions, the analysis of gas mixture revealed that each target component was well-separated with high selectivity property. The method was also found to be precise and accurate. The method linearity was found to be high with good correlation coefficient values (R2 ≥ 0.999) for all target components. It can be concluded that the GC-FID developed method is reliable and suitable for determination of light C2-C4 hydrocarbons (including ethylene, propane, propylene, isobutane, and n-butane) in their gas mixture. The validated method has successfully been applied to the estimation of hydrocarbons light C2-C4 hydrocarbons in natural gas samples, showing high performance repeatability with relative standard deviation (RSD) less than 1.0% and good selectivity with no interference from other possible components could be observed.http://revistas.unal.edu.co/index.php/rcolquim/article/view/58085method validationhydrocarbonsGC-FIDISO/IEC 17025 |
| spellingShingle | Oman Zuas Harry budiman Muhammad Rizky Mulyana Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture Revista Colombiana de Química method validation hydrocarbons GC-FID ISO/IEC 17025 |
| title | Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture |
| title_full | Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture |
| title_fullStr | Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture |
| title_full_unstemmed | Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture |
| title_short | Analytical method validation of GC-FID for the simultaneous measurement of hydrocarbons (C2-C4) in their gas mixture |
| title_sort | analytical method validation of gc fid for the simultaneous measurement of hydrocarbons c2 c4 in their gas mixture |
| topic | method validation hydrocarbons GC-FID ISO/IEC 17025 |
| url | http://revistas.unal.edu.co/index.php/rcolquim/article/view/58085 |
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