“The Silk Road” via subarachnoid cisterns
Meningiomas are generally slow-growing extra-axial benign tumours and in rare cases they can metastasize both neural and extra-neural. Intracranial meningiomas with leptomeningeal dissemination are extremely rare and the exact pathogenesis still remains unknown. The aim of this review is to analyse...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
London Academic Publishing
2019-09-01
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| Series: | Romanian Neurosurgery |
| Subjects: | |
| Online Access: | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1176 |
| _version_ | 1818210521946521600 |
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| author | A. I. Cucu Mihaela Dana Turliuc Claudia Florida Costea B. Costăchescu Cristina Mihaela Ghiciuc B. Dobrovăț Camelia Margareta Bogdănici Daniela Maria Tănase Gabriela Florența Dumitrescu Anca Sava I. Poeată |
| author_facet | A. I. Cucu Mihaela Dana Turliuc Claudia Florida Costea B. Costăchescu Cristina Mihaela Ghiciuc B. Dobrovăț Camelia Margareta Bogdănici Daniela Maria Tănase Gabriela Florența Dumitrescu Anca Sava I. Poeată |
| author_sort | A. I. Cucu |
| collection | DOAJ |
| description | Meningiomas are generally slow-growing extra-axial benign tumours and in rare cases they can metastasize both neural and extra-neural. Intracranial meningiomas with leptomeningeal dissemination are extremely rare and the exact pathogenesis still remains unknown. The aim of this review is to analyse the pathways of intracranial and spinal metastatic spread of intracranial meningiomas and to discuss their particular clinical and pathological features. We highlight the fact that there is a possibility of leptomeningeal dissemination, even if cerebrospinal fluid cytology is negative, in patients with a medical history of a resected meningioma. We identified three possible ways of dissemination: haematogenous, through the CSF, or during surgery. From a histopathological point of view, the more malignant the meningioma, the more likely its leptomeningeal dissemination. |
| first_indexed | 2024-12-12T05:17:56Z |
| format | Article |
| id | doaj.art-08a7d15c99e94c698c17da5af646a3aa |
| institution | Directory Open Access Journal |
| issn | 1220-8841 2344-4959 |
| language | English |
| last_indexed | 2024-12-12T05:17:56Z |
| publishDate | 2019-09-01 |
| publisher | London Academic Publishing |
| record_format | Article |
| series | Romanian Neurosurgery |
| spelling | doaj.art-08a7d15c99e94c698c17da5af646a3aa2022-12-22T00:36:43ZengLondon Academic PublishingRomanian Neurosurgery1220-88412344-49592019-09-0133310.33962/roneuro-2019-043“The Silk Road” via subarachnoid cisternsA. I. CucuMihaela Dana TurliucClaudia Florida CosteaB. CostăchescuCristina Mihaela GhiciucB. DobrovățCamelia Margareta BogdăniciDaniela Maria TănaseGabriela Florența DumitrescuAnca SavaI. PoeatăMeningiomas are generally slow-growing extra-axial benign tumours and in rare cases they can metastasize both neural and extra-neural. Intracranial meningiomas with leptomeningeal dissemination are extremely rare and the exact pathogenesis still remains unknown. The aim of this review is to analyse the pathways of intracranial and spinal metastatic spread of intracranial meningiomas and to discuss their particular clinical and pathological features. We highlight the fact that there is a possibility of leptomeningeal dissemination, even if cerebrospinal fluid cytology is negative, in patients with a medical history of a resected meningioma. We identified three possible ways of dissemination: haematogenous, through the CSF, or during surgery. From a histopathological point of view, the more malignant the meningioma, the more likely its leptomeningeal dissemination.https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1176meningiomametastatic spreadCSF disseminated meningioma |
| spellingShingle | A. I. Cucu Mihaela Dana Turliuc Claudia Florida Costea B. Costăchescu Cristina Mihaela Ghiciuc B. Dobrovăț Camelia Margareta Bogdănici Daniela Maria Tănase Gabriela Florența Dumitrescu Anca Sava I. Poeată “The Silk Road” via subarachnoid cisterns Romanian Neurosurgery meningioma metastatic spread CSF disseminated meningioma |
| title | “The Silk Road” via subarachnoid cisterns |
| title_full | “The Silk Road” via subarachnoid cisterns |
| title_fullStr | “The Silk Road” via subarachnoid cisterns |
| title_full_unstemmed | “The Silk Road” via subarachnoid cisterns |
| title_short | “The Silk Road” via subarachnoid cisterns |
| title_sort | the silk road via subarachnoid cisterns |
| topic | meningioma metastatic spread CSF disseminated meningioma |
| url | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1176 |
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