Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments

The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvatu...

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Bibliographic Details
Main Authors: Peng Xie, Heng Zhang, Yatong Qin, Hehe Xiong, Changrong Shi, Zijian Zhou
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/12/1772
Description
Summary:The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvature and its association with membrane proteins. Furthermore, we delve into the impact and potential implications of this interaction in the context of disease treatment. Lastly, we discuss the prospects and challenges associated with harnessing these interactions for effective disease management, aiming to provide fresh insights into therapeutic strategies.
ISSN:2218-273X