Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments
The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvatu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/13/12/1772 |
| _version_ | 1797381779111280640 |
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| author | Peng Xie Heng Zhang Yatong Qin Hehe Xiong Changrong Shi Zijian Zhou |
| author_facet | Peng Xie Heng Zhang Yatong Qin Hehe Xiong Changrong Shi Zijian Zhou |
| author_sort | Peng Xie |
| collection | DOAJ |
| description | The pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvature and its association with membrane proteins. Furthermore, we delve into the impact and potential implications of this interaction in the context of disease treatment. Lastly, we discuss the prospects and challenges associated with harnessing these interactions for effective disease management, aiming to provide fresh insights into therapeutic strategies. |
| first_indexed | 2024-03-08T20:57:22Z |
| format | Article |
| id | doaj.art-08a9be7712714554a254a5c593364d9e |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-08T20:57:22Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-08a9be7712714554a254a5c593364d9e2023-12-22T13:56:04ZengMDPI AGBiomolecules2218-273X2023-12-011312177210.3390/biom13121772Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease TreatmentsPeng Xie0Heng Zhang1Yatong Qin2Hehe Xiong3Changrong Shi4Zijian Zhou5State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Shenzhen Research Institute of Xiamen University, Xiamen University, Xiamen 361102, ChinaThe pathogenesis of various diseases often involves an intricate interplay between membrane proteins and membrane curvature. Understanding the underlying mechanisms of this interaction could offer novel perspectives on disease treatment. In this review, we provide an introduction to membrane curvature and its association with membrane proteins. Furthermore, we delve into the impact and potential implications of this interaction in the context of disease treatment. Lastly, we discuss the prospects and challenges associated with harnessing these interactions for effective disease management, aiming to provide fresh insights into therapeutic strategies.https://www.mdpi.com/2218-273X/13/12/1772membrane proteinmembrane curvatureinteractiondisease treatment |
| spellingShingle | Peng Xie Heng Zhang Yatong Qin Hehe Xiong Changrong Shi Zijian Zhou Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments Biomolecules membrane protein membrane curvature interaction disease treatment |
| title | Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments |
| title_full | Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments |
| title_fullStr | Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments |
| title_full_unstemmed | Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments |
| title_short | Membrane Proteins and Membrane Curvature: Mutual Interactions and a Perspective on Disease Treatments |
| title_sort | membrane proteins and membrane curvature mutual interactions and a perspective on disease treatments |
| topic | membrane protein membrane curvature interaction disease treatment |
| url | https://www.mdpi.com/2218-273X/13/12/1772 |
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