Prospects of conservative treatment for Clostridium septicum–associated aortitis

Clostridium septicum bacteremia is a rare (72 cases reported) aneurysm-inducing disease that has resulted in a 6-month mortality of 100% when treated conservatively. We report the case of a patient who was completely symptom free at 6 months of follow-up but who ultimately died at 8.9 months after a...

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Main Authors: Patrick Kirchweger, MD, Helwig Wundsam, MD, Felix Bosse, MD, Alexander Kupferthaler, MD, Reinhold Huemer, MD, Reinhold Függer, MD
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468428722000399
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author Patrick Kirchweger, MD
Helwig Wundsam, MD
Felix Bosse, MD
Alexander Kupferthaler, MD
Reinhold Huemer, MD
Reinhold Függer, MD
author_facet Patrick Kirchweger, MD
Helwig Wundsam, MD
Felix Bosse, MD
Alexander Kupferthaler, MD
Reinhold Huemer, MD
Reinhold Függer, MD
author_sort Patrick Kirchweger, MD
collection DOAJ
description Clostridium septicum bacteremia is a rare (72 cases reported) aneurysm-inducing disease that has resulted in a 6-month mortality of 100% when treated conservatively. We report the case of a patient who was completely symptom free at 6 months of follow-up but who ultimately died at 8.9 months after aortic rupture. In compliance with the patient’s choice, a long-time antibiotic regimen was applied, instead of the surgical approach recommended by our surgical department. The use of an antibiotic regimen represents an option for patients unfit for surgery or as a bridge to surgery for damage control; however, aortic repair represents the only curative approach. Definitive antibiotic treatment is limited to a palliative approach for patients with C. septicum aortitis and has been accompanied by 100% 1-year mortality (90-day mortality, 84.2%).
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spelling doaj.art-08ab96e33c324f31a3f0b879c79bdb802022-12-22T03:32:09ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872022-06-0182227231Prospects of conservative treatment for Clostridium septicum–associated aortitisPatrick Kirchweger, MD0Helwig Wundsam, MD1Felix Bosse, MD2Alexander Kupferthaler, MD3Reinhold Huemer, MD4Reinhold Függer, MD5Department of Surgery, Ordensklinikum Linz, Linz, Austria; Johannes Kepler University Linz, Medical Faculty, Linz, Austria; Correspondence: Patrick Kirchweger, MD, Department of Surgery, Ordensklinikum Linz, Seilerstätte 4, Linz 4010, AustriaDepartment of Surgery, Ordensklinikum Linz, Linz, AustriaDepartment of Surgery, Ordensklinikum Linz, Linz, AustriaDepartment of Diagnostic and Interventional Radiology, Ordensklinikum Linz, Linz, AustriaDepartment of Vascular Surgery, Brothers of Saint John of God, Linz, AustriaDepartment of Surgery, Ordensklinikum Linz, Linz, Austria; Johannes Kepler University Linz, Medical Faculty, Linz, AustriaClostridium septicum bacteremia is a rare (72 cases reported) aneurysm-inducing disease that has resulted in a 6-month mortality of 100% when treated conservatively. We report the case of a patient who was completely symptom free at 6 months of follow-up but who ultimately died at 8.9 months after aortic rupture. In compliance with the patient’s choice, a long-time antibiotic regimen was applied, instead of the surgical approach recommended by our surgical department. The use of an antibiotic regimen represents an option for patients unfit for surgery or as a bridge to surgery for damage control; however, aortic repair represents the only curative approach. Definitive antibiotic treatment is limited to a palliative approach for patients with C. septicum aortitis and has been accompanied by 100% 1-year mortality (90-day mortality, 84.2%).http://www.sciencedirect.com/science/article/pii/S2468428722000399Abdominal aneurysmAortitisCase reportClostridium septicumOccult colonic malignancy
spellingShingle Patrick Kirchweger, MD
Helwig Wundsam, MD
Felix Bosse, MD
Alexander Kupferthaler, MD
Reinhold Huemer, MD
Reinhold Függer, MD
Prospects of conservative treatment for Clostridium septicum–associated aortitis
Journal of Vascular Surgery Cases and Innovative Techniques
Abdominal aneurysm
Aortitis
Case report
Clostridium septicum
Occult colonic malignancy
title Prospects of conservative treatment for Clostridium septicum–associated aortitis
title_full Prospects of conservative treatment for Clostridium septicum–associated aortitis
title_fullStr Prospects of conservative treatment for Clostridium septicum–associated aortitis
title_full_unstemmed Prospects of conservative treatment for Clostridium septicum–associated aortitis
title_short Prospects of conservative treatment for Clostridium septicum–associated aortitis
title_sort prospects of conservative treatment for clostridium septicum associated aortitis
topic Abdominal aneurysm
Aortitis
Case report
Clostridium septicum
Occult colonic malignancy
url http://www.sciencedirect.com/science/article/pii/S2468428722000399
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