Diffuse lipomatosis of the thyroid gland: A pathologic curiosity

We report the case of a 45-year-old man who presented with a 4-year history of midline neck swelling associated with recent onset respiratory distress. Local examination showed a lobulated diffuse thyroid enlargement. A subtotal thyroidectomy was performed. The right lobe weighed 225 g and the left...

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Main Authors: Gupta Ruchika, Arora Raman, Sharma Alok, Dinda Amit
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-04-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=215;epage=216;aulast=Gupta
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author Gupta Ruchika
Arora Raman
Sharma Alok
Dinda Amit
author_facet Gupta Ruchika
Arora Raman
Sharma Alok
Dinda Amit
author_sort Gupta Ruchika
collection DOAJ
description We report the case of a 45-year-old man who presented with a 4-year history of midline neck swelling associated with recent onset respiratory distress. Local examination showed a lobulated diffuse thyroid enlargement. A subtotal thyroidectomy was performed. The right lobe weighed 225 g and the left lobe weighed 130 g. Multiple sections from both the lobes revealed diffuse infiltration of the stroma by mature adipose tissue. There was no evidence of amyloid deposits or papillary carcinoma. A final diagnosis of diffuse lipomatosis of the thyroid gland was rendered. Lipomatosis or adenolipomatosis of the thyroid gland is an extremely rare entity. The various differential diagnoses of fat in the thyroid include benign entities like amyloid goiter, adenolipoma, lymphocytic thyroiditis, intrathyroid thymic or parathyroid lipoma and malignant tumors like liposarcoma and encapsulated papillary carcinoma. Adequate clinical details and a thorough histopathological examination are mandatory for diagnosis.
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spelling doaj.art-08ae64413ddc44e289479b2388d981a32022-12-22T01:28:38ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292009-04-01522215216Diffuse lipomatosis of the thyroid gland: A pathologic curiosityGupta RuchikaArora RamanSharma AlokDinda AmitWe report the case of a 45-year-old man who presented with a 4-year history of midline neck swelling associated with recent onset respiratory distress. Local examination showed a lobulated diffuse thyroid enlargement. A subtotal thyroidectomy was performed. The right lobe weighed 225 g and the left lobe weighed 130 g. Multiple sections from both the lobes revealed diffuse infiltration of the stroma by mature adipose tissue. There was no evidence of amyloid deposits or papillary carcinoma. A final diagnosis of diffuse lipomatosis of the thyroid gland was rendered. Lipomatosis or adenolipomatosis of the thyroid gland is an extremely rare entity. The various differential diagnoses of fat in the thyroid include benign entities like amyloid goiter, adenolipoma, lymphocytic thyroiditis, intrathyroid thymic or parathyroid lipoma and malignant tumors like liposarcoma and encapsulated papillary carcinoma. Adequate clinical details and a thorough histopathological examination are mandatory for diagnosis.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=215;epage=216;aulast=GuptaHistopathologylipomatosisthyroid
spellingShingle Gupta Ruchika
Arora Raman
Sharma Alok
Dinda Amit
Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
Indian Journal of Pathology and Microbiology
Histopathology
lipomatosis
thyroid
title Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
title_full Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
title_fullStr Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
title_full_unstemmed Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
title_short Diffuse lipomatosis of the thyroid gland: A pathologic curiosity
title_sort diffuse lipomatosis of the thyroid gland a pathologic curiosity
topic Histopathology
lipomatosis
thyroid
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=215;epage=216;aulast=Gupta
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AT aroraraman diffuselipomatosisofthethyroidglandapathologiccuriosity
AT sharmaalok diffuselipomatosisofthethyroidglandapathologiccuriosity
AT dindaamit diffuselipomatosisofthethyroidglandapathologiccuriosity