Correlation between homocysteine levels and stroke in patients with acute ischemic stroke
Ischemic strokes are mostly caused by atherosclerosis, and increased homocysteine levels are considered to play a role in atherosclerosis. The aim of this study was to investigate serum total homocysteine (tHcy) levels in the first 24 h of ischemic stroke patients and to analyze the correlation betw...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2019-03-01
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| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=13370 |
| _version_ | 1827360477064200192 |
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| author | Adnan Kirmit Aysegul Akagunduz Ege Ali Guctekin Mustafa Kemal Basarili Mujgan Ercan Karadag |
| author_facet | Adnan Kirmit Aysegul Akagunduz Ege Ali Guctekin Mustafa Kemal Basarili Mujgan Ercan Karadag |
| author_sort | Adnan Kirmit |
| collection | DOAJ |
| description | Ischemic strokes are mostly caused by atherosclerosis, and increased homocysteine levels are considered to play a role in atherosclerosis. The aim of this study was to investigate serum total homocysteine (tHcy) levels in the first 24 h of ischemic stroke patients and to analyze the correlation between tHcy levels and the clinical severity of ischemic stroke. The study included a total of 151 participants including a patient group of 83 patients diagnosed with acute ischemic stroke and a control group of 68 age- and gender-matched subjects with no history of ischemic vascular diseases between June 2006 and December 2007. Demographic characteristics of were recorded for each participant and stroke severity was assessed using the modified Rankin Scale (mRS) in each patient. Serum tHcy, vitamin B12, folic acid, and fibrinogen levels as well as platelet count and lipid profiles were measured for each participant. Serum tHcy levels were significantly higher and the folic acid levels were significantly lower in the patient group compared to the control group (p [Med-Science 2019; 8(1.000): 11-5] |
| first_indexed | 2024-03-08T06:47:48Z |
| format | Article |
| id | doaj.art-08b0c7213cef470e8c771815beca4652 |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T06:47:48Z |
| publishDate | 2019-03-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-08b0c7213cef470e8c771815beca46522024-02-03T07:29:02ZengSociety of Turaz BilimMedicine Science2147-06342019-03-018111510.5455/medscience.2018.07.893213370Correlation between homocysteine levels and stroke in patients with acute ischemic strokeAdnan Kirmit0Aysegul Akagunduz Ege1Ali Guctekin2Mustafa Kemal Basarili3Mujgan Ercan Karadag4Harran University Medical Faculty, Department of Biochemistry, Sanliurfa, Turkey Kulu State Hospital, Konya, Turkey Department of Biochemistry, Ankara Numune Training and Research Hospital, Ankara, Turkey Ministry of Health, Turkish Public Health Institution , Ankara , Turkey Harran University Medical Faculty, Department of Biochemistry, Sanliurfa, TurkeyIschemic strokes are mostly caused by atherosclerosis, and increased homocysteine levels are considered to play a role in atherosclerosis. The aim of this study was to investigate serum total homocysteine (tHcy) levels in the first 24 h of ischemic stroke patients and to analyze the correlation between tHcy levels and the clinical severity of ischemic stroke. The study included a total of 151 participants including a patient group of 83 patients diagnosed with acute ischemic stroke and a control group of 68 age- and gender-matched subjects with no history of ischemic vascular diseases between June 2006 and December 2007. Demographic characteristics of were recorded for each participant and stroke severity was assessed using the modified Rankin Scale (mRS) in each patient. Serum tHcy, vitamin B12, folic acid, and fibrinogen levels as well as platelet count and lipid profiles were measured for each participant. Serum tHcy levels were significantly higher and the folic acid levels were significantly lower in the patient group compared to the control group (p [Med-Science 2019; 8(1.000): 11-5]http://www.ejmanager.com/fulltextpdf.php?mno=13370Acute ischemic strokemodified rankin coma scalehomocysteinevascular risk factors |
| spellingShingle | Adnan Kirmit Aysegul Akagunduz Ege Ali Guctekin Mustafa Kemal Basarili Mujgan Ercan Karadag Correlation between homocysteine levels and stroke in patients with acute ischemic stroke Medicine Science Acute ischemic stroke modified rankin coma scale homocysteine vascular risk factors |
| title | Correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| title_full | Correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| title_fullStr | Correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| title_full_unstemmed | Correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| title_short | Correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| title_sort | correlation between homocysteine levels and stroke in patients with acute ischemic stroke |
| topic | Acute ischemic stroke modified rankin coma scale homocysteine vascular risk factors |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=13370 |
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