On the Significance of Fuzzification of the N and M in Cancer Staging
The tumor, node, metastasis (TNM) staging system has been regarded as one of the most widely used staging systems for solid cancer. The “T” is assigned a value according to the primary tumor size, whereas the “N” and “M” are dependent on the number of regional lymph nodes and the presence of distant...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2014-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S13765 |
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author | Sara A. Yones Ahmed S. Moussa Hesham Hassan Nelly H. Alieldin |
author_facet | Sara A. Yones Ahmed S. Moussa Hesham Hassan Nelly H. Alieldin |
author_sort | Sara A. Yones |
collection | DOAJ |
description | The tumor, node, metastasis (TNM) staging system has been regarded as one of the most widely used staging systems for solid cancer. The “T” is assigned a value according to the primary tumor size, whereas the “N” and “M” are dependent on the number of regional lymph nodes and the presence of distant metastasis, respectively. The current TNM model classifies stages into five crisp classes. This is unrealistic since the drastic modification in treatment that is based on a change in one class may be based on a slight shift around the class boundary. Moreover, the system considers any tumor that has distant metastasis as stage 4, disregarding the metastatic lesion concentration and size. We had handled the problem of T staging in previous studies using fuzzy logic. In this study, we focus on the fuzzification of N and M staging for more accurate and realistic modeling which may, in turn, lead to better treatment and medical decisions. |
first_indexed | 2024-12-24T04:58:04Z |
format | Article |
id | doaj.art-08b4254722804627b4a00c9673ff54e2 |
institution | Directory Open Access Journal |
issn | 1176-9351 |
language | English |
last_indexed | 2024-12-24T04:58:04Z |
publishDate | 2014-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Cancer Informatics |
spelling | doaj.art-08b4254722804627b4a00c9673ff54e22022-12-21T17:14:19ZengSAGE PublishingCancer Informatics1176-93512014-01-011310.4137/CIN.S13765On the Significance of Fuzzification of the N and M in Cancer StagingSara A. Yones0Ahmed S. Moussa1Hesham Hassan2Nelly H. Alieldin3Computer Science Department, Faculty of Computers and Information, Cairo University, Egypt.Computer Science Department, Faculty of Computers and Information, Cairo University, Egypt.Computer Science Department, Faculty of Computers and Information, Cairo University, Egypt.Department of Statistics, National Cancer Institute, Cairo University, Egypt.The tumor, node, metastasis (TNM) staging system has been regarded as one of the most widely used staging systems for solid cancer. The “T” is assigned a value according to the primary tumor size, whereas the “N” and “M” are dependent on the number of regional lymph nodes and the presence of distant metastasis, respectively. The current TNM model classifies stages into five crisp classes. This is unrealistic since the drastic modification in treatment that is based on a change in one class may be based on a slight shift around the class boundary. Moreover, the system considers any tumor that has distant metastasis as stage 4, disregarding the metastatic lesion concentration and size. We had handled the problem of T staging in previous studies using fuzzy logic. In this study, we focus on the fuzzification of N and M staging for more accurate and realistic modeling which may, in turn, lead to better treatment and medical decisions.https://doi.org/10.4137/CIN.S13765 |
spellingShingle | Sara A. Yones Ahmed S. Moussa Hesham Hassan Nelly H. Alieldin On the Significance of Fuzzification of the N and M in Cancer Staging Cancer Informatics |
title | On the Significance of Fuzzification of the N and M in Cancer Staging |
title_full | On the Significance of Fuzzification of the N and M in Cancer Staging |
title_fullStr | On the Significance of Fuzzification of the N and M in Cancer Staging |
title_full_unstemmed | On the Significance of Fuzzification of the N and M in Cancer Staging |
title_short | On the Significance of Fuzzification of the N and M in Cancer Staging |
title_sort | on the significance of fuzzification of the n and m in cancer staging |
url | https://doi.org/10.4137/CIN.S13765 |
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