EEG markers of cognitive impairments in patients with coronary artery disease
Objective: to identify the indicators of bioelectrical activity of the cerebral cortex, which are associated with cognitive impairments in patients with coronary artery disease (CAD).Patients and methods. The study included 122 male patients aged 45 to 69 years with CAD. Sixty of them were found to...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2016-11-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
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| Online Access: | https://nnp.ima-press.net/nnp/article/view/645 |
| _version_ | 1827062882927378432 |
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| author | I. V. Tarasova I. N. Kukhareva O. L. Barbarash |
| author_facet | I. V. Tarasova I. N. Kukhareva O. L. Barbarash |
| author_sort | I. V. Tarasova |
| collection | DOAJ |
| description | Objective: to identify the indicators of bioelectrical activity of the cerebral cortex, which are associated with cognitive impairments in patients with coronary artery disease (CAD).Patients and methods. The study included 122 male patients aged 45 to 69 years with CAD. Sixty of them were found to have mild cognitive impairments (MCI), their average Mini-Mental State Examination (MMSE) score was 26.2±0.90; the other 62 patients had no cognitive impairment; their MMSE score was 28.5±0.86. All the patients underwent clinical and instrumental examinations and computer-based multichannel electroencephalography (EEG). Eyes-closed and eyes-open resting EEG monopolarly recorded in 62 standard leads of the 10-20 system. A binary logistic regression analysis was used to identify EEG predictors of MCI in patients with CAD.Results. The high power values of theta1-rhythm biopotentials with closed eyes in the frontal and occipital areas of the left hemisphere and those of alpha2-rhythm ones with open eyes in the frontal areas of the right hemisphere, and the high theta/alpha EEG power ratio are associated with an increased risk of MCI in CAD patients. The most important clinical and anamnestic factors associated with a decreased risk of MCI were higher education level, the lack of type 2 diabetes, and milder coronary bed lesions according to the SYNTAX scale. There was an association of the power values of the biopotentials and theta/alpha EEG power ratio and the development of MCI in CAD patients. |
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| format | Article |
| id | doaj.art-08b52ba9e8ca464cb1c96821565afba1 |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2025-02-18T20:02:56Z |
| publishDate | 2016-11-01 |
| publisher | IMA-PRESS LLC |
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| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-08b52ba9e8ca464cb1c96821565afba12024-10-17T16:15:23ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422016-11-0183434710.14412/2074-2711-2016-3-43-47584EEG markers of cognitive impairments in patients with coronary artery diseaseI. V. Tarasova0I. N. Kukhareva1O. L. Barbarash2Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia 6, Sosnovyi Boulevard, Kemerovo 650002Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia 6, Sosnovyi Boulevard, Kemerovo 650002Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia 6, Sosnovyi Boulevard, Kemerovo 650002Objective: to identify the indicators of bioelectrical activity of the cerebral cortex, which are associated with cognitive impairments in patients with coronary artery disease (CAD).Patients and methods. The study included 122 male patients aged 45 to 69 years with CAD. Sixty of them were found to have mild cognitive impairments (MCI), their average Mini-Mental State Examination (MMSE) score was 26.2±0.90; the other 62 patients had no cognitive impairment; their MMSE score was 28.5±0.86. All the patients underwent clinical and instrumental examinations and computer-based multichannel electroencephalography (EEG). Eyes-closed and eyes-open resting EEG monopolarly recorded in 62 standard leads of the 10-20 system. A binary logistic regression analysis was used to identify EEG predictors of MCI in patients with CAD.Results. The high power values of theta1-rhythm biopotentials with closed eyes in the frontal and occipital areas of the left hemisphere and those of alpha2-rhythm ones with open eyes in the frontal areas of the right hemisphere, and the high theta/alpha EEG power ratio are associated with an increased risk of MCI in CAD patients. The most important clinical and anamnestic factors associated with a decreased risk of MCI were higher education level, the lack of type 2 diabetes, and milder coronary bed lesions according to the SYNTAX scale. There was an association of the power values of the biopotentials and theta/alpha EEG power ratio and the development of MCI in CAD patients.https://nnp.ima-press.net/nnp/article/view/645electroencephalographytheta/alpha ratiocognitive impairmentscoronary artery disease |
| spellingShingle | I. V. Tarasova I. N. Kukhareva O. L. Barbarash EEG markers of cognitive impairments in patients with coronary artery disease Неврология, нейропсихиатрия, психосоматика electroencephalography theta/alpha ratio cognitive impairments coronary artery disease |
| title | EEG markers of cognitive impairments in patients with coronary artery disease |
| title_full | EEG markers of cognitive impairments in patients with coronary artery disease |
| title_fullStr | EEG markers of cognitive impairments in patients with coronary artery disease |
| title_full_unstemmed | EEG markers of cognitive impairments in patients with coronary artery disease |
| title_short | EEG markers of cognitive impairments in patients with coronary artery disease |
| title_sort | eeg markers of cognitive impairments in patients with coronary artery disease |
| topic | electroencephalography theta/alpha ratio cognitive impairments coronary artery disease |
| url | https://nnp.ima-press.net/nnp/article/view/645 |
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