The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i>
Sericin derived from the white cocoon of <i>Bombyx mori</i> has been attracting more attention for its utilization in food, cosmetics, and biomedicine. The potential health benefits of natural carotenoids for humans have also been well-established. Some rare strains of <i>Bombyx mo...
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2024-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/25/7/3688 |
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| author | Sirui Liu Qing Zhang Hanyue Zhou Bo Zhang Ming Yu Yonglong Wang Yanqun Liu Chunli Chai |
| author_facet | Sirui Liu Qing Zhang Hanyue Zhou Bo Zhang Ming Yu Yonglong Wang Yanqun Liu Chunli Chai |
| author_sort | Sirui Liu |
| collection | DOAJ |
| description | Sericin derived from the white cocoon of <i>Bombyx mori</i> has been attracting more attention for its utilization in food, cosmetics, and biomedicine. The potential health benefits of natural carotenoids for humans have also been well-established. Some rare strains of <i>Bombyx mori</i> (<i>B. mori</i>) produce yellow–red cocoons, which endow a potential of natural carotenoid-containing sericin. We hypothesized that natural carotenoid-containing sericin from yellow–red cocoons would exhibit better properties compared with white cocoon sericin. To investigate the physicochemical attributes of natural carotenoid-containing sericin, we bred two silkworm strains from one common ancestor, namely XS7 and XS8, which exhibited different cocoon colors as a result of the inconsistent distribution of lutein and β-carotene. Compared with white cocoon sericin, the interaction between carotenoids and sericin molecules in carotenoid-containing sericin resulted in a unique fluorescence emission at 530, 564 nm. The incorporation of carotenoids enhanced the antibacterial effect, anti-cancer ability, cytocompatibility, and antioxidant of sericin, suggesting potential wide-ranging applications of natural carotenoid-containing sericin as a biomass material. We also found differences in fluorescence characteristics, antimicrobial effects, anti-cancer ability, and antioxidants between XS7 and XS8 sericin. Our work for the first time suggested a better application potential of natural carotenoid-containing sericin as a biomass material than frequently used white cocoon sericin. |
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| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-04-24T10:42:55Z |
| publishDate | 2024-03-01 |
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| series | International Journal of Molecular Sciences |
| spelling | doaj.art-08bd3cbd575043c296e49d9f064991442024-04-12T13:19:28ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672024-03-01257368810.3390/ijms25073688The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i>Sirui Liu0Qing Zhang1Hanyue Zhou2Bo Zhang3Ming Yu4Yonglong Wang5Yanqun Liu6Chunli Chai7College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaCollege of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 111000, ChinaState Key Laboratory of Resource Insects, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaSericin derived from the white cocoon of <i>Bombyx mori</i> has been attracting more attention for its utilization in food, cosmetics, and biomedicine. The potential health benefits of natural carotenoids for humans have also been well-established. Some rare strains of <i>Bombyx mori</i> (<i>B. mori</i>) produce yellow–red cocoons, which endow a potential of natural carotenoid-containing sericin. We hypothesized that natural carotenoid-containing sericin from yellow–red cocoons would exhibit better properties compared with white cocoon sericin. To investigate the physicochemical attributes of natural carotenoid-containing sericin, we bred two silkworm strains from one common ancestor, namely XS7 and XS8, which exhibited different cocoon colors as a result of the inconsistent distribution of lutein and β-carotene. Compared with white cocoon sericin, the interaction between carotenoids and sericin molecules in carotenoid-containing sericin resulted in a unique fluorescence emission at 530, 564 nm. The incorporation of carotenoids enhanced the antibacterial effect, anti-cancer ability, cytocompatibility, and antioxidant of sericin, suggesting potential wide-ranging applications of natural carotenoid-containing sericin as a biomass material. We also found differences in fluorescence characteristics, antimicrobial effects, anti-cancer ability, and antioxidants between XS7 and XS8 sericin. Our work for the first time suggested a better application potential of natural carotenoid-containing sericin as a biomass material than frequently used white cocoon sericin.https://www.mdpi.com/1422-0067/25/7/3688sericincarotenoidsphysicochemical properties |
| spellingShingle | Sirui Liu Qing Zhang Hanyue Zhou Bo Zhang Ming Yu Yonglong Wang Yanqun Liu Chunli Chai The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> International Journal of Molecular Sciences sericin carotenoids physicochemical properties |
| title | The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> |
| title_full | The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> |
| title_fullStr | The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> |
| title_full_unstemmed | The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> |
| title_short | The Potential of Natural Carotenoids-Containing Sericin of the Domestic Silkworm <i>Bombyx mori</i> |
| title_sort | potential of natural carotenoids containing sericin of the domestic silkworm i bombyx mori i |
| topic | sericin carotenoids physicochemical properties |
| url | https://www.mdpi.com/1422-0067/25/7/3688 |
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