Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association

Primary ciliary dyskinesia (PCD) is a congenital disorder characterized by abnormal ciliary motility with associated impaired mucociliary clearance. When PCD has associated situs inversus, it is known as Kartagener's disease. Due to recurrent sinopulmonary infections, patients of Kartagener...

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Main Authors: Govindaraj Vishnukanth, Dharm Prakash Dwivedi, Aneesa Shahul, Ravindra Chary Mulkoju, Jyotirmaya Sahoo
Format: Article
Language:English
Published: Jaypee Brothers Medical Publisher 2019-01-01
Series:Indian Journal of Respiratory Care
Subjects:
Online Access:http://www.ijrconline.org/article.asp?issn=2277-9019;year=2019;volume=8;issue=2;spage=118;epage=120;aulast=
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author Govindaraj Vishnukanth
Dharm Prakash Dwivedi
Aneesa Shahul
Ravindra Chary Mulkoju
Jyotirmaya Sahoo
author_facet Govindaraj Vishnukanth
Dharm Prakash Dwivedi
Aneesa Shahul
Ravindra Chary Mulkoju
Jyotirmaya Sahoo
author_sort Govindaraj Vishnukanth
collection DOAJ
description Primary ciliary dyskinesia (PCD) is a congenital disorder characterized by abnormal ciliary motility with associated impaired mucociliary clearance. When PCD has associated situs inversus, it is known as Kartagener's disease. Due to recurrent sinopulmonary infections, patients of Kartagener's disease develop bronchiectasis. Allergic bronchopulmonary aspergillosis (ABPA) is an allergic disorder characterized by exaggerated immune response to the fungus Aspergillus. Patients with ABPA also develop bronchiectasis in advanced stages. Here, we report a patient of Kartagener's disease who also had coexisting ABPA. We believe such an association has been reported in just a handful of cases. As Kartagener's disease can be easily diagnosed radiologically and bronchiectasis is a feature of Kartagener's disease, many of these patients do not undergo further evaluation. In reporting this rare occurrence, we believe many such associations will be revealed in future.
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spelling doaj.art-08bd4f52b4f94b7f9125544e621aa2622023-09-03T13:26:40ZengJaypee Brothers Medical PublisherIndian Journal of Respiratory Care2277-90192321-48992019-01-018211812010.4103/ijrc.ijrc_29_18Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual associationGovindaraj VishnukanthDharm Prakash DwivediAneesa ShahulRavindra Chary MulkojuJyotirmaya SahooPrimary ciliary dyskinesia (PCD) is a congenital disorder characterized by abnormal ciliary motility with associated impaired mucociliary clearance. When PCD has associated situs inversus, it is known as Kartagener's disease. Due to recurrent sinopulmonary infections, patients of Kartagener's disease develop bronchiectasis. Allergic bronchopulmonary aspergillosis (ABPA) is an allergic disorder characterized by exaggerated immune response to the fungus Aspergillus. Patients with ABPA also develop bronchiectasis in advanced stages. Here, we report a patient of Kartagener's disease who also had coexisting ABPA. We believe such an association has been reported in just a handful of cases. As Kartagener's disease can be easily diagnosed radiologically and bronchiectasis is a feature of Kartagener's disease, many of these patients do not undergo further evaluation. In reporting this rare occurrence, we believe many such associations will be revealed in future.http://www.ijrconline.org/article.asp?issn=2277-9019;year=2019;volume=8;issue=2;spage=118;epage=120;aulast=Allergic bronchopulmonary aspergillosisprimary ciliary dyskinesiasitus inversus
spellingShingle Govindaraj Vishnukanth
Dharm Prakash Dwivedi
Aneesa Shahul
Ravindra Chary Mulkoju
Jyotirmaya Sahoo
Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
Indian Journal of Respiratory Care
Allergic bronchopulmonary aspergillosis
primary ciliary dyskinesia
situs inversus
title Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
title_full Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
title_fullStr Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
title_full_unstemmed Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
title_short Allergic bronchopulmonary aspergillosis in a patient with kartagener's disease: An unusual association
title_sort allergic bronchopulmonary aspergillosis in a patient with kartagener s disease an unusual association
topic Allergic bronchopulmonary aspergillosis
primary ciliary dyskinesia
situs inversus
url http://www.ijrconline.org/article.asp?issn=2277-9019;year=2019;volume=8;issue=2;spage=118;epage=120;aulast=
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AT aneesashahul allergicbronchopulmonaryaspergillosisinapatientwithkartagenersdiseaseanunusualassociation
AT ravindracharymulkoju allergicbronchopulmonaryaspergillosisinapatientwithkartagenersdiseaseanunusualassociation
AT jyotirmayasahoo allergicbronchopulmonaryaspergillosisinapatientwithkartagenersdiseaseanunusualassociation