Multiplex PCR-Based Neutralization (MPBN) Assay for Titers Determination of the Three Types of Anti-Poliovirus Neutralizing-Antibodies

Multiplex PCR-Based Neutralization (MPBN) Assay for Titers Determination of the Three Types of Anti-Poliovirus Neutralizing-Antibodies

Determination of poliovirus-neutralizing antibodies is an important part of clinical studies of poliovirus vaccines, epidemiological surveillance and seroprevalence studies that are crucial for global polio eradication campaigns. The conventional neutralization test is based on inhibition of cytopat...

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Bibliographic Details
Main Authors: Hasmik Manukyan, Svetlana Petrovskaya, Konstantin Chumakov, Majid Laassri
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
neutralization
anti-poliovirus antibodies seroprevalence
opv
ipv
clinical trials
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/8/1/120

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