β Cell function and plasma insulin clearance in people with obesity and different glycemic status
Background It is unclear how excess adiposity and insulin resistance affect β cell function, insulin secretion, and insulin clearance in people with obesity.Methods We used a hyperinsulinemic-euglycemic clamp procedure and a modified oral glucose tolerance test to evaluate the interrelationships amo...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-02-01
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Series: | The Journal of Clinical Investigation |
Subjects: | |
Online Access: | https://doi.org/10.1172/JCI154068 |