MiR-378a-5p Regulates Proliferation and Migration in Vascular Smooth Muscle Cell by Targeting CDK1

MiR-378a-5p Regulates Proliferation and Migration in Vascular Smooth Muscle Cell by Targeting CDK1

Objective: Abnormal proliferation or migration of vascular smooth muscle cells (VSMCs) can lead to vessel lesions, resulting in atherosclerosis and in stent-restenosis (IRS). The purpose of our study was to establish the role of miR-378a-5p and its targets in regulating VSMCs function and IRS.Method...

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Bibliographic Details
Main Authors: Shaoyan Liu, Yanyan Yang, Shaoyan Jiang, Hong Xu, Ningning Tang, Amara Lobo, Rui Zhang, Song Liu, Tao Yu, Hui Xin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
miR-378a-5p
vascular smooth muscle cell
stent-restenosis
proliferation
migration
atherosclerosis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00022/full

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