Mechanism of Action and Clinical Potential of Fingolimod for the Treatment of Stroke

Mechanism of Action and Clinical Potential of Fingolimod for the Treatment of Stroke

Fingolimod (FTY720) is an orally bio-available immunomodulatory drug currently approved by the FDA for the treatment of multiple sclerosis. Currently, there is a significant interest in the potential benefits of FTY720 on stroke outcomes. FTY720 and the sphingolipid signaling pathway it modulates ha...

Full description

Bibliographic Details
Main Authors: Wentao Li, Haoliang Xu, Fernando Daniel Testai
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Neurology
Subjects:
Stroke
Neuroprotection
hemorrhagic stroke
ischemic stroke
Sphingosine-1-phosphate
vascular endothelium
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00139/full

Similar Items

Similar Items