Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey
The present study aimed to evaluate patients who were referred to adult allergy clinic due to allergic reactions after concomitant multiple intravenous-drug administrations in Emergency Department (ED). Between January 2017 and January 2019, patients admitted to our allergy clinic with hypersensitiv...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2021-09-01
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| Series: | Emergency Care Journal |
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| Online Access: | https://pagepressjournals.org/index.php/ecj/article/view/9848 |
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| author | Mehmet Erdem Çakmak Saltuk Buğra Kaya Özge Can Bostan Ebru Damadoğlu Gül Karakaya Ali Fuat Kalyoncu |
| author_facet | Mehmet Erdem Çakmak Saltuk Buğra Kaya Özge Can Bostan Ebru Damadoğlu Gül Karakaya Ali Fuat Kalyoncu |
| author_sort | Mehmet Erdem Çakmak |
| collection | DOAJ |
| description | The present study aimed to evaluate patients who were referred to adult allergy clinic due to allergic reactions after concomitant multiple intravenous-drug administrations in Emergency Department (ED). Between January 2017 and January 2019, patients admitted to our allergy clinic with hypersensitivity reactions to intravenous drugs administered in ED were included retrospectively. Fifty-seven patients who developed allergic reactions after intravenous drug administration in EDs were evaluated. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) were the most common cause of allergic reactions (n = 40, 70.2%). Skin Prick Tests (SPT) were positive in 6 (10.5%) patients. Drug Provocation Tests (DPT) were positive in 10 (17.5%) patients. No significant correlation was found between the total number of drugs in the intravenous fluid and the degree of allergic reaction (r = -0.145, p = 0.282). There was no statistically significant difference between the degree of allergic reaction and history of atopic disease (p = 0.579). In conclusion, concomitant administration of multiple drugs in intravenous fluids may increase the risk of allergic reactions. |
| first_indexed | 2024-04-13T07:23:07Z |
| format | Article |
| id | doaj.art-08c3a7fe28f246b38b45860d938d16d0 |
| institution | Directory Open Access Journal |
| issn | 1826-9826 2282-2054 |
| language | English |
| last_indexed | 2024-04-13T07:23:07Z |
| publishDate | 2021-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Emergency Care Journal |
| spelling | doaj.art-08c3a7fe28f246b38b45860d938d16d02022-12-22T02:56:33ZengPAGEPress PublicationsEmergency Care Journal1826-98262282-20542021-09-0117310.4081/ecj.2021.9848Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in TurkeyMehmet Erdem Çakmak0Saltuk Buğra Kaya1Özge Can Bostan2Ebru Damadoğlu3Gül Karakaya4Ali Fuat Kalyoncu5Clinic of Allergy and Clinical Immunology, Başakşehir Çam ve Sakura City Hospital, IstanbulClinic of Allergy and Clinical Immunology, Erzurum Training and Research Hospital, ErzurumDepartment of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University School of Medicine, AnkaraDepartment of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University School of Medicine, AnkaraDepartment of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University School of Medicine, AnkaraDepartment of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University School of Medicine, AnkaraThe present study aimed to evaluate patients who were referred to adult allergy clinic due to allergic reactions after concomitant multiple intravenous-drug administrations in Emergency Department (ED). Between January 2017 and January 2019, patients admitted to our allergy clinic with hypersensitivity reactions to intravenous drugs administered in ED were included retrospectively. Fifty-seven patients who developed allergic reactions after intravenous drug administration in EDs were evaluated. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) were the most common cause of allergic reactions (n = 40, 70.2%). Skin Prick Tests (SPT) were positive in 6 (10.5%) patients. Drug Provocation Tests (DPT) were positive in 10 (17.5%) patients. No significant correlation was found between the total number of drugs in the intravenous fluid and the degree of allergic reaction (r = -0.145, p = 0.282). There was no statistically significant difference between the degree of allergic reaction and history of atopic disease (p = 0.579). In conclusion, concomitant administration of multiple drugs in intravenous fluids may increase the risk of allergic reactions.https://pagepressjournals.org/index.php/ecj/article/view/9848Drug allergydrug hypersensitivityemergency medicinefluid therapyintravenous infusion |
| spellingShingle | Mehmet Erdem Çakmak Saltuk Buğra Kaya Özge Can Bostan Ebru Damadoğlu Gül Karakaya Ali Fuat Kalyoncu Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey Emergency Care Journal Drug allergy drug hypersensitivity emergency medicine fluid therapy intravenous infusion |
| title | Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey |
| title_full | Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey |
| title_fullStr | Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey |
| title_full_unstemmed | Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey |
| title_short | Allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in Turkey |
| title_sort | allergic reactions due to concomitant administration of multiple drugs in intravenous fluid in emergency departments in turkey |
| topic | Drug allergy drug hypersensitivity emergency medicine fluid therapy intravenous infusion |
| url | https://pagepressjournals.org/index.php/ecj/article/view/9848 |
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