The Need for Actions Against Polypharmacy in Older People With Frailty

Providing safe and effective drug therapy to older patients is challenging for physicians since there is not sufficient evidence to support the efficacy of these drugs and this population is susceptible to adverse drug reactions. Special consideration is needed when treating patients who require nur...

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Main Author: Taro Kojima
Format: Article
Language:English
Published: Korea Geriatrics Society 2018-09-01
Series:Annals of Geriatric Medicine and Research
Subjects:
Online Access:http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.3.111
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author Taro Kojima
author_facet Taro Kojima
author_sort Taro Kojima
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description Providing safe and effective drug therapy to older patients is challenging for physicians since there is not sufficient evidence to support the efficacy of these drugs and this population is susceptible to adverse drug reactions. Special consideration is needed when treating patients who require nursing care or who are at a stage prior to disability (i.e., frailty) because they may have limited life expectancies, complications, or organ dysfunction. Polypharmacy refers to the condition in which a patient is taking many drugs and, thus, is at an increased risk of adverse events. Although it is difficult to avoid polypharmacy in older people with frailty, the periodic review of drugs and reduction of dose or discontinuation of potentially inappropriate medications are needed to address this problem. This article reviews the association between frailty and polypharmacy and counteractions against polypharmacy in patients with frailty.
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spelling doaj.art-08c43f765a8d47a8ae19a0e5e3ff354c2022-12-21T21:43:26ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982018-09-0122311111610.4235/agmr.2018.22.3.111agmr.2018.22.3.111The Need for Actions Against Polypharmacy in Older People With FrailtyTaro Kojima0Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanProviding safe and effective drug therapy to older patients is challenging for physicians since there is not sufficient evidence to support the efficacy of these drugs and this population is susceptible to adverse drug reactions. Special consideration is needed when treating patients who require nursing care or who are at a stage prior to disability (i.e., frailty) because they may have limited life expectancies, complications, or organ dysfunction. Polypharmacy refers to the condition in which a patient is taking many drugs and, thus, is at an increased risk of adverse events. Although it is difficult to avoid polypharmacy in older people with frailty, the periodic review of drugs and reduction of dose or discontinuation of potentially inappropriate medications are needed to address this problem. This article reviews the association between frailty and polypharmacy and counteractions against polypharmacy in patients with frailty.http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.3.111PolypharmacyDrug therapyFrailtyPotentially inappropriate medications
spellingShingle Taro Kojima
The Need for Actions Against Polypharmacy in Older People With Frailty
Annals of Geriatric Medicine and Research
Polypharmacy
Drug therapy
Frailty
Potentially inappropriate medications
title The Need for Actions Against Polypharmacy in Older People With Frailty
title_full The Need for Actions Against Polypharmacy in Older People With Frailty
title_fullStr The Need for Actions Against Polypharmacy in Older People With Frailty
title_full_unstemmed The Need for Actions Against Polypharmacy in Older People With Frailty
title_short The Need for Actions Against Polypharmacy in Older People With Frailty
title_sort need for actions against polypharmacy in older people with frailty
topic Polypharmacy
Drug therapy
Frailty
Potentially inappropriate medications
url http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.3.111
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