Co-inhibition of adenosine 2b receptor and programmed death-ligand 1 promotes the recruitment and cytotoxicity of natural killer cells in oral squamous cell carcinoma

Co-inhibition of adenosine 2b receptor and programmed death-ligand 1 promotes the recruitment and cytotoxicity of natural killer cells in oral squamous cell carcinoma

Adenosine promotes anti-tumor immune responses by modulating the functions of T-cells and natural killer (NK) cells in the tumor microenvironment; however, the role of adenosine receptors in the progression of oral squamous cell carcinoma (OSCC) and its effects on immune checkpoint therapy remain un...

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Bibliographic Details
Main Authors: Bing Wang, Tao Wang, Chengzhe Yang, Zhaodi Nan, Dan Ai, Xin Wang, Huayang Wang, Xun Qu, Fengcai Wei
Format: Article
Language:English
Published: PeerJ Inc. 2023-08-01
Series:PeerJ
Subjects:
Oral squamous cell carcinoma
Checkpoint inhibitor
PD-L1
A2BR
NK cell
Online Access:https://peerj.com/articles/15922.pdf

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https://peerj.com/articles/15922.pdf

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