Co-inhibition of adenosine 2b receptor and programmed death-ligand 1 promotes the recruitment and cytotoxicity of natural killer cells in oral squamous cell carcinoma
Adenosine promotes anti-tumor immune responses by modulating the functions of T-cells and natural killer (NK) cells in the tumor microenvironment; however, the role of adenosine receptors in the progression of oral squamous cell carcinoma (OSCC) and its effects on immune checkpoint therapy remain un...
Main Authors: | Bing Wang, Tao Wang, Chengzhe Yang, Zhaodi Nan, Dan Ai, Xin Wang, Huayang Wang, Xun Qu, Fengcai Wei |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2023-08-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/15922.pdf |
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